Melphalan EP Impurity J CAS 2724549-95-3

Purity >95%In StockPharmacopoeial Impurity Standards
CAS No.2724549-95-3
Molecular FormulaC15H22Cl2N2O3
Molecular Weight349.25 g/mol
CategoryPharmacopoeial Impurity Standards / EP Impurities
AvailabilityIn Stock

Chemical Structure

Melphalan EP Impurity J CAS 2724549-95-3 chemical structure

Description

Compared with other compounds in its class, the molecular weight of 349.25 g/mol gives Melphalan EP Impurity J distinctive chromatographic separation conditions and mass-spectrometry parameter settings.

Melphalan EP Impurity J (CAS 2724549-95-3) is a certified pharmaceutical impurity reference standard with the molecular formula C15H22Cl2N2O3 and a molecular weight of 349.25 g/mol.

Melphalan EP Impurity J (C15H22Cl2N2O3) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. It is notably hygroscopic, halogen substitution raises its density and boiling point, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.

Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.

As a certified reference material (CRM), Melphalan EP Impurity J meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.

Physical & Chemical Properties

Molecular FormulaC15H22Cl2N2O3
Molecular Weight349.25 g/mol
AppearanceOff-white to pale yellow crystalline powder. (slight halide-like odor, low volatility)
Purity>95%
StorageStore at 2-8°C, protect from light, keep sealed and dry
Solubility (reference)Soluble in DMSO, DMF, methanol
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions
Degree of Unsaturation (DBE)5.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)2002
Halogen ContentCl-containing
Nitrogen Atoms2

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