trans-3-benzyloxy-1-hydroxy-cyclobutanecarboxylic acid CAS 2725791-21-7
| CAS No. | 2725791-21-7 |
| Molecular Formula | C12H20O4 |
| Molecular Weight | 228.28 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 228.28 g/mol gives trans-3-benzyloxy-1-hydroxy-cyclobutanecarboxylic acid distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
trans-3-benzyloxy-1-hydroxy-cyclobutanecarboxylic acid (CAS 2725791-21-7), molecular formula C12H20O4 and molecular weight 228.28 g/mol, is a CATO reference standard with documented purity and traceability.
The molecular framework of trans-3-benzyloxy-1-hydroxy-cyclobutanecarboxylic acid (C12H20O4) is characterized by a carboxylic acid group, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C12H20O4 |
| Molecular Weight | 228.28 g/mol |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), keep sealed and dry |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 3.0 |
| UV Absorption | UV-absorbing |
| CAS Registry Year (est.) | 2002 |
Related trans Standards
- cis-3-benzyloxy-1-hydroxy-cyclobutanecarboxylic acid (CAS 2293093-37-3)
- 5-(Benzyloxy)-N,N-dimethylpyridin-2-amine (CAS 1083329-09-2)
- (R)-1-(4-(Benzyloxy)phenyl)ethan-1-ol (CAS 118239-25-1)
- (1S)-1-[4-(Benzyloxy)phenyl]ethan-1-ol (CAS 119776-17-9)
- (1S)-1-[2-(benzyloxy)phenyl]ethan-1-ol (CAS 1212083-48-1)
- (1S)-1-[3-(benzyloxy)phenyl]ethan-1-ol (CAS 1280591-41-4)
- 1-(Benzyloxy)-2-(methoxymethyl)benzene (CAS 128145-50-6)
- (1r)-1-[3-(benzyloxy)phenyl]ethan-1-ol (CAS 1354485-14-5)
Recommended Standards
- trans 4-(Tetrahydropyran-2-yloxy)-cyclohexanecarboxylic acid (CAS 2089620-04-0)
- 2-Hydroxycyclohexanone dimer 30282-14-5 Adipoin NSC 117392 (CAS 30282-14-5)
- Sodium 5-Amino-6-ethoxynaphthalene-2-sulfonate (CAS 84145-62-0)
- 3-[2-(2-carboxyethyl)phenyl]propanoic acid 3-[2-(3-hydroxy-3-oxopropyl)phenyl]propanoic acid 4251-21-2 A825918 (CAS 4251-21-2)
- Allyl ethenesulfonate (CAS 7459-72-5)
- 2-Fluoro-4-(3-methylphenyl)benzonitrile (CAS 1381944-81-5)
- 8-Methyl-8-nonenoic acid (CAS 42150-00-5)
- 1-(6-(Cyclopropylamino)-2-(methylthio)pyrimidin-4-yl)piperidin-4-ol (CAS 1353977-27-1)
- 2-(Chloromethyl)-5,6-di(thiophen-2-yl)furo[2,3-d]pyrimidin-4-amine (CAS 1000933-79-8)
- 1,2-Dimethyl-3-propylimidazolium tris(trifluoromethylsulfonyl)methide 1,2-dimethyl-3-propyl-1H-imidazol-3-ium tris(trifluoromethylsulfonyl)methanide 169051-77-8 (CAS 169051-77-8)
- 2-(2-Chloro-4-nitrophenoxy)-N-(1-cyanocyclohexyl)acetamide (CAS 852226-84-7)
- 7-Bromo-2-chloro-1H-indole (CAS 1782043-07-5)
- 4,6-Dimethylpyrimidine-2-carboxamide (CAS 73937-25-4)
- Semaglutide impurity 44 (CAS CATO-C4X-222644)
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