Tropicamide Impurity 20 CAS 2727060-69-5
| CAS No. | 2727060-69-5 |
| Molecular Formula | C17H20N2O3 |
| Molecular Weight | 300.35 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
Tropicamide Impurity 20 (CAS 2727060-69-5) is a certified pharmaceutical impurity reference standard with the molecular formula C17H20N2O3 and a molecular weight of 300.35 g/mol.
The molecular framework of Tropicamide Impurity 20 (C17H20N2O3) is characterized by a steroid core, an amide group, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
As a certified reference material (CRM), Tropicamide Impurity 20 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C17H20N2O3 |
| Molecular Weight | 300.35 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | ≥95% |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 9.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2002 |
| Nitrogen Atoms | 2 |
Related Tropicamide Standards
- Tropicamide Impurity 16 (CAS 1184914-87-1)
- Tropicamide (CAS 1508-75-4)
- Tropicamide Impurity 19 (CAS CATO-C4X-215019)
- Tropicamide EP Impurity B (CAS 57322-50-6)
- Tropicamide Impurity 11 (CAS 101112-51-0)
- Tropicamide Impurity 17 (CAS CATO-C4X-215017)
- Tropicamide Impurity 13 (CAS CATO-C4X-215013)
- Tropicamide Impurity 21 (CAS 96392-48-2)
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