1-(4-Fluorophenyl)hexan-1-amine hydrochloride CAS 2728-89-4
| CAS No. | 2728-89-4 |
| Molecular Formula | C12H18FN |
| Molecular Weight | N/A |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of 1-(4-Fluorophenyl)hexan-1-amine hydrochloride is closely related to a nitrile group, fluorine/chlorine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
1-(4-Fluorophenyl)hexan-1-amine hydrochloride (CAS 2728-89-4) is a high-purity analytical reference standard with the molecular formula C12H18FNHCl and a molecular weight of 231.74 g/mol.
The molecular framework of 1-(4-Fluorophenyl)hexan-1-amine hydrochloride (C12H18FNHCl) is characterized by a nitrile group, fluorine/chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C12H18FN HCl |
| Molecular Weight | 231.74 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 3.0 |
| UV Absorption | UV-absorbing |
| CAS Registry Year (est.) | 1957 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 1 |
Related Fluorophenyl Standards
- 3-[(3-fluorophenyl)methyl]pyrrolidine (CAS 1000198-80-0)
- 3-(3-Fluorophenyl)-3-oxopropanoic acid (CAS 1000530-96-0)
- Ethyl 1-(4-fluorophenyl)-5-oxo-2,5-dihydro-1H-1,2,4-triazole-3-carboxylate (CAS 1000573-68-1)
- 1000574-26-4 2-(4-Fluorophenyl)-6-methylthio-4H-thiopyran-4-one MFCD09877819 (CAS 1000574-26-4)
- Ethyl 1-(2-fluorophenyl)-5-oxo-2,5-dihydro-1H-1,2,4-triazole-3-carboxylate (CAS 1000575-18-7)
- 100074-04-2 5-(4-Fluorophenyl)-1-pentene MFCD11553774 (CAS 100074-04-2)
- 3-(2-Fluorophenyl)-4-hydroxyfuran-2(5H)-one (CAS 100074-44-0)
- N-[2-(4-fluorophenyl)ethyl]-1H-imidazole-1-carboxamide (CAS 1000931-75-8)
Recommended Standards
- (2-Bromo-5-methoxypyridin-4-yl)methanol (CAS 1806982-66-0)
- N-(1-(pyridin-4-yl)ethyl)tetrahydro-2H-thiopyran-4-amine (CAS 1153144-95-6)
- 3-(Trifluoromethyl)-N'-(3-(trifluoromethyl)phenyl)benzimidamide (CAS 339027-02-0)
- 1-(2-Methylpropyl)-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazole (CAS 847818-75-1)
- 1-(3,4-Dimethylphenyl)propan-1-one (CAS 17283-12-4)
- a-Me-Phe(4-Ph)-OH·H2O (CAS 1231709-24-2)
- (±)-11-Hydroxy-Δ9-THC (CAS 34675-49-5)
- (R)-1-Aminooxy-propan-2-ol (CAS 338464-47-4)
- 1-Bromo-3-fluoro-5-methyl-2-nitrobenzene (CAS 1806979-54-3)
- Serpent Peptide (CAS 823202-99-9)
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