7-Bromo-2,4,6-trichloro-8-fluoroquinoline-3-carbaldehyde CAS 2728716-42-3
| CAS No. | 2728716-42-3 |
| Molecular Formula | C10H2BrCl3FNO |
| Molecular Weight | 357.39 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 7-Bromo-2,4,6-trichloro-8-fluoroquinoline-3-carbaldehyde.
CATO supplies 7-Bromo-2,4,6-trichloro-8-fluoroquinoline-3-carbaldehyde (CAS 2728716-42-3), a certified reference material (molecular formula C10H2BrCl3FNO, MW 357.39 g/mol) for analytical method development and quality control.
The molecular framework of 7-Bromo-2,4,6-trichloro-8-fluoroquinoline-3-carbaldehyde (C10H2BrCl3FNO) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine/chlorine/bromine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C10H2BrCl3FNO |
| Molecular Weight | 357.39 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2002 |
| Halogen Content | F/Cl/Br-containing |
| Nitrogen Atoms | 1 |
Related Bromo Standards
- 7-Bromo-2,4,6-trichloro-3-nitro-1,5-naphthyridine (CAS 2918766-35-3)
- 6-Bromo-4-chloro-3-iodo-1H-pyrrolo[2,3-b]pyridine (CAS 1000340-68-0)
- 4-Bromo-6-chloro-3-iodo-1H-pyrrolo[2,3-b]pyridine (CAS 1000340-78-2)
- 4-Bromo-7-chloro-3-iodo-1H-pyrrolo[3,2-c]pyridine (CAS 1000341-91-2)
- 7-Bromo-4-chloro-3-iodo-1H-pyrrolo[3,2-c]pyridine (CAS 1000342-07-3)
- 5-Bromo-4-chloro-3-iodo-1H-pyrrolo[2,3-b]pyridine (CAS 1092579-75-3)
- 3-Bromo-6-chloro-8-iodoimidazo[1,2-a]pyridine (CAS 1221791-77-0)
- 6-Bromo-3-chloro-8-iodo-imidazo[1,2-a]pyridine (CAS 1296223-94-3)
Recommended Standards
- 5-(Benzyl(tert-butoxycarbonyl)amino)-4,4-difluoro-2-methylpentanoic acid (CAS 2101206-20-4)
- Ethyl 3-oxo-4-((3-(pyridin-2-yl)-[1,2,4]triazolo[4,3-b]pyridazin-6-yl)thio)butanoate (CAS 868968-29-0)
- 2-{phenyl[(1,3-thiazol-2-yl)amino]phosphoroso}-1,3-benzothiazole (CAS 262603-96-3)
- Methyl 2-{[(4E)-5-oxo-4-{[4-(1H-1,2,4-triazol-1-yl)phenyl]methylidene}-4,5-dihydro-1H-imidazol-2-yl]sulfanyl}propanoate (CAS 860784-29-8)
- 2-Diisopropylaminoethyl Ester Xanthene-9-carboxylic Acid Hydrochloride (CAS 102476-84-6)
- 8-Chloro-[1,2,4]triazolo[1,5-a]pyridine (CAS 1427368-62-4)
- 3-(bromomethyl)-2-methylpyridine hydrobromide (CAS 1384972-82-0)
- Isopropyl 2-bromo-5-(trifluoromethyl)benzoate (CAS 1506090-22-7)
- (4-Methyl-2-(1H-pyrazol-1-yl)pyrimidin-5-yl)boronic acid (CAS 2225179-93-9)
- Chlorphenamine Impurity 24 (CAS CATO-C4X-118824)
- 3-(4-Fluorophenyl)-5-methyl-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine (CAS 439107-88-7)
- 7-Methoxy-3-(((4-methoxyphenyl)amino)methyl)quinolin-2-ol (CAS 335222-91-8)
- tert-Butyl (1-(5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridin-2-yl)pyrrolidin-3-yl)carbamate (CAS 1357397-73-9)
- Semaglutide impurity 269 (CAS CATO-C4X-2226269)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com