Boc-Phe(3-I)-OH CAS 273221-75-3
| CAS No. | 273221-75-3 |
| Molecular Formula | C14H18INO4 |
| Molecular Weight | 391.20 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Boc-Phe(3-I)-OH (CAS 273221-75-3), molecular formula C14H18INO4 and molecular weight 391.20 g/mol, is a CATO reference standard with documented purity and traceability.
The molecular framework of Boc-Phe(3-I)-OH (C14H18INO4) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, iodine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C14H18INO4 |
| Molecular Weight | 391.20 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | I-containing |
| Nitrogen Atoms | 1 |
Recommended Standards
- Boc-Phe(2-I)-OH (CAS 273221-78-6)
- ethyl 1-(iodomethyl)-3-oxazol-2-yl-2-oxabicyclo[2.2.2]octane-4-carboxylate (CAS 2703779-86-4)
- Boc-D-Phe(2-I)-OH (CAS 478183-64-1)
- Methyl 4-(2-chlorophenoxy)-1-(4-chlorophenyl)-6-oxo-1,6-dihydropyridazine-3-carboxylate (CAS 338405-72-4)
- 4-(2-Aminoethylthio)-6-bromo-2-(trifluoromethyl)quinoline (CAS 541539-72-4)
- rel-(2R,3R)-3-Amino-2-hydroxy-3-(2-(trifluoromethyl)phenyl)propanoic acid (CAS 1217690-64-6)
- Ethyl 1-oxo-2,3-dihydro-1H-indene-4-carbimidothioate (CAS 138764-35-9)
- N-Methyl-N-(tetrahydrofuran-3-yl)piperidin-4-amine (CAS 1257293-66-5)
- 1-Bromo-5-fluoro-3-iodo-2-methylbenzene (CAS 1805552-81-1)
- 4-(1-Methyl-1h-1,2,3-triazol-5-yl)benzoic acid (CAS 1067614-15-6)
- (E)-4-(4-(trifluoromethyl)pyridin-2-yl)benzaldehyde O-(3-methoxybenzyl) oxime (CAS 1092343-86-6)
- 2-(2-Aminoethyl)-3-fluorobenzonitrile hydrochloride (CAS 1188263-91-3)
- Ricamycin (CAS 74014-51-0)
- Des-Val23-Tirzepatide (CAS CATO-CPTD788950)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com