(2S,4R)-1-[(tert-butoxy)carbonyl]-4-(hydroxymethyl)pyrrolidine-2-carboxylic acid CAS 273221-97-9
| CAS No. | 273221-97-9 |
| Molecular Formula | C11H19NO5 |
| Molecular Weight | 245.27 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
(2S,4R)-1-[(tert-butoxy)carbonyl]-4-(hydroxymethyl)pyrrolidine-2-carboxylic acid (CAS 273221-97-9) is a high-purity analytical reference standard with the molecular formula C11H19NO5 and a molecular weight of 245.27 g/mol.
The molecular framework of (2S,4R)-1-[(tert-butoxy)carbonyl]-4-(hydroxymethyl)pyrrolidine-2-carboxylic acid (C11H19NO5) is characterized by an amino-acid-derived structure, an amide group, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
As a certified reference material (CRM), (2S,4R)-1-[(tert-butoxy)carbonyl]-4-(hydroxymethyl)pyrrolidine-2-carboxylic acid meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C11H19NO5 |
| Molecular Weight | 245.27 g/mol |
| Appearance | White to pale yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 3.0 |
| UV Absorption | UV-absorbing |
| CAS Registry Year (est.) | 2025 |
| Nitrogen Atoms | 1 |
Recommended Standards
- (2S,4R)-1-(tert-Butoxycarbonyl)-4-methoxypyrrolidine-2-carboxylic acid (CAS 83624-01-5)
- (2S,4R)-4-{[(tert-butoxy)carbonyl]amino}oxane-2-carboxylic acid (CAS 2306245-87-2)
- (2S,4R)-1-(tert-Butoxycarbonyl)-4-hydroxypiperidine-2-carboxylic acid (CAS 955016-25-8)
- (2S,4S)-1-(tert-Butoxycarbonyl)-4-hydroxypiperidine-2-carboxylic acid (CAS 441044-12-8)
- 2,2'-(Methylenebis(oxy))bis(ethan-1-ol) (CAS 2565-36-8)
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