2-Chloro-4-(trifluoromethyl)thiophen-3-amine hydrochloride CAS 2732241-87-9
| CAS No. | 2732241-87-9 |
| Molecular Formula | C5H3ClF3NS |
| Molecular Weight | N/A |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
As a certified reference material (CRM), 2-Chloro-4-(trifluoromethyl)thiophen-3-amine hydrochloride meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
2-Chloro-4-(trifluoromethyl)thiophen-3-amine hydrochloride (CAS 2732241-87-9) is a high-purity analytical reference standard with the molecular formula C5H3ClF3NSHCl and a molecular weight of 238.05 g/mol.
The molecular framework of 2-Chloro-4-(trifluoromethyl)thiophen-3-amine hydrochloride (C5H3ClF3NSHCl) is characterized by a nitrile group, sulfur-containing functionality, fluorine/chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
Physical & Chemical Properties
| Molecular Formula | C5H3ClF3NS HCl |
| Molecular Weight | 238.05 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO |
| Stability | Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 2.0 |
| CAS Registry Year (est.) | 2002 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 1 |
| Sulfur Atoms | 1 |
Related Chloro Standards
- benzyl 4-(5-chloro-1-(2-ethoxy-2-oxoethyl)-6-oxo-1,6-dihydropyridazin-4-yl)piperazine-1-carboxylate (CAS 1000018-18-7)
- 3-[(2-Chloro-4-methylsulfonyl)phenoxy]benzoic acid (CAS 1000018-31-4)
- 6-Chloro-2-[2-(3-[(6-chloro-1-ethylbenz[c,d,]indole-2[1H]-ylidene)ethylidene]-2-phenyl-1-cyclopenten-1-yl)ethenyl]-1-ethylbenz[c,d]indolium tetrafluoroborate (CAS 100012-45-1)
- 3-Chloro-2-fluoro-5-iodobenzoic acid (CAS 1000162-09-3)
- (3-Chloro-2-fluoro-5-iodophenyl)methanol (CAS 1000162-10-6)
- 3-Chloro-2-fluoro-5-nitrobenzoic acid (CAS 1000162-34-4)
- 2-Chloro-N-(piperidin-4-yl)-6,7-dihydro-5H-cyclopenta-[d]pyrimidin-4-amine hydrochloride (CAS 1000207-51-1)
- 4-chloro-6-(3,3-difluoropyrrolidin-1-yl)pyrimidine (CAS 1000303-40-1)
Recommended Standards
- (S)-1-(4-Fluorophenyl)propan-1-amine (CAS 473732-86-4)
- (7s,8As)-7-fluorooctahydropyrrolo[1,2-a]pyrazine (CAS 1222712-17-5)
- Musk Tibeten (CAS 145-39-1)
- 2-Amino-N-phenylbenzene-1-sulfonamide (CAS 27332-20-3)
- (8-Methyl-8-azabicyclo[3.2.1]oct-3-yl)methanamine (CAS 1137476-92-6)
- 7-Chloro-2-ethyl-5-fluorobenzofuran (CAS 847867-07-6)
- Chloro(dimethyl)octylsilane (CAS 18162-84-0)
- tert-Butyl N-(2-oxo-1,2-dihydropyridin-4-yl)carbamate (CAS 1363383-37-2)
- Ethyl (5-(acridin-9-ylamino)-2-methylphenyl)carbamate (CAS 655238-70-3)
- Peptide Impurity 28 (CAS 1350456-64-2)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com