Selexipag Impurity 4 CAS 2732400-56-3
| CAS No. | 2732400-56-3 |
| Molecular Formula | C25H29N3O4 |
| Molecular Weight | 435.52 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
As a process- or degradation-related impurity, Selexipag Impurity 4 (CAS 2732400-56-3, C25H29N3O4) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Selexipag Impurity 4 (C25H29N3O4) contains a flavonoid core, an amide group, a hydroxyl group, an ether linkage. It is notably hygroscopic, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
As a certified reference material (CRM), Selexipag Impurity 4 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C25H29N3O4 |
| Molecular Weight | 435.52 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | >95% |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 13.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2002 |
| Nitrogen Atoms | 3 |
Related Selexipag Standards
- Selexipag Impurity 71 (CAS CATO-C4X-196171)
- Selexipag Impurity 24 (CAS 475086-96-5)
- Selexipag Impurity 42 (CAS CATO-C4X-196142)
- Selexipag Impurity 2 D6 (CAS 1265295-56-4)
- Selexipag Impurity 5 (CAS 2287345-22-4)
- Selexipag Impurity 2 (CAS 475085-57-5)
- Selexipag Impurity 17 (CAS 475086-28-3)
- Selexipag Impurity 59 (CAS CATO-C4X-196159)
Recommended Standards
- Valsartan Impurity 58 (CAS CATO-C4X-105758)
- Finerenone Impurity 102 (CAS CATO-C4X-2880102)
- Valsartan Impurity 102 (CAS CATO-C4X-1057102)
- Finerenone Impurity 77 (CAS CATO-C4X-288077)
- Desonide Impurity 9 (CAS 117782-94-2)
- Propranolol Impurity 9 (CAS 4662-18-4)
- Prednisone Impurity 9 (CAS 2435-02-1)
- Vonoprazan Fumarate Impurity 24 (CAS 881733-45-5（free base）)
- methyl 3-hydroxy-1-(2-methylpropanoyl)cyclobutane-1-carboxylate (CAS 1515561-54-2)
- 3-Amino-4-methoxybenzaldehyde (CAS 351003-10-6)
- 2-Bromopyrazolo[1,5-a]pyrimidine-6-carboxylic acid (CAS 1783552-72-6)
- 4-Chloro-7-methyl-2-(pyridin-2-yl)indoline (CAS 594820-93-6)
- Myoseverin (CAS 267402-71-1)
- Pancreatic Polypeptide (human) trifluoroacetate salt (CAS 75976-10-2)
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