4-Chloro-1-methyl-5-azaindole CAS 27382-01-0
| CAS No. | 27382-01-0 |
| Molecular Formula | C8H7ClN2 |
| Molecular Weight | 166.61 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 4-Chloro-1-methyl-5-azaindole.
4-Chloro-1-methyl-5-azaindole (CAS 27382-01-0), molecular formula C8H7ClN2 and molecular weight 166.61 g/mol, is a CATO reference standard with documented purity and traceability.
Structurally, 4-Chloro-1-methyl-5-azaindole (C8H7ClN2) contains a nitrogen-containing heterocyclic scaffold, a nitrile group, chlorine substitution. The molecule exhibits a degree of unsaturation (DBE) of 6.0, corresponding to approximately 6 ring(s) or double-bond equivalent(s). With a molecular weight of 166.61 g/mol, it falls into the medium-molecular-weight range. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C8H7ClN2 |
| Molecular Weight | 166.61 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1964 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 2 |
Related Chloro Standards
- 5-Chloro-6-methyl-1H-pyrrolo[2,3-b]pyridine (CAS 1000340-18-0)
- 6-Chloro-5-methyl-1H-indazole (CAS 1000341-02-5)
- 3-Chloro-7-methyl-1H-pyrrolo[3,2-c]pyridine (CAS 1000341-46-7)
- 5-Chloro-6-methyl-2H-indazole (CAS 1000343-64-5)
- 2-(2-Chloro-6-methylpyridin-3-yl)acetonitrile (CAS 1000514-91-9)
- 2-(6-Chloro-2-methylpyridin-3-yl)acetonitrile (CAS 1000529-85-0)
- 6-Chloro-2,4-dimethylpyridine-3-carbonitrile (CAS 101251-72-3)
- 2-Chloro-6-Methylimidazo[1,2-a]pyridine (CAS 1019019-96-5)
Recommended Standards
- 4-Chloro-1-methyl-1H-benzo[d]imidazole (CAS 75438-01-6)
- 4-Chloro-2,6-dimethylpyridine-3-carbonitrile (CAS 91591-61-6)
- 4-Chloro-1H-indol-6-amine (CAS 885520-22-9)
- 4-Chloro-2-methyl-1H-benzo[d]imidazole (CAS 5599-82-6)
- N-Nitrosodiisodecylamin (CAS CATO-C3D-26155)
- 3,5-Dimethyl-1-(2-(trifluoromethoxy)ethyl)-1h-pyrazol-4-amine (CAS 1489065-03-3)
- Ethyl 2-(1,4-diazepan-1-yl)acetate (CAS 913645-28-0)
- 2-Chloro-3-(pyrrolidin-1-yl)naphthalene-1,4-dione (CAS 59641-25-7)
- 1-(pyrrolidin-1-ylcarbonyl)piperidine-3-carboxylic acid (CAS 1017668-81-3)
- NPS ALX Compound 4a dihydrochloride (CAS 1781934-44-8)
- 2,2,2-Trifluoroacetic acid compound with 2-(azetidin-3-yl)propanoic acid (1:1) (CAS 1797923-92-2)
- 4-(Tetramethyl-1,3,2-dioxaborolan-2-yl)-2,1,3-benzothiadiazole (CAS 1088118-97-1)
- 3-(3-Thienylmethyl)azetidine 3-(thien-3-ylmethyl)azetidine 929974-86-7 (CAS 929974-86-7)
- Endo-Gly4-Semaglutide (CAS CATO-C4X-222679)
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