Imidazo[1,5-a]pyrimidine CAS 274-67-9

Description

Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including Imidazo[1,5-a]pyrimidine.

Imidazo[1,5-a]pyrimidine (CAS 274-67-9), molecular formula C6H5N3 and molecular weight 119.12 g/mol, is a CATO reference standard with documented purity and traceability.

Owing to a nitrile group, an aromatic ring system, Imidazo[1,5-a]pyrimidine is typically off-white to pale yellow liquid. Its solid-state physicochemical attributes — including a molecular weight of 119.12 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.

Physical & Chemical Properties

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