5-Bromo-2-(2,6-dioxopiperidin-3-yl)-4-fluoroisoindoline-1,3-dione CAS 2740657-28-5
| CAS No. | 2740657-28-5 |
| Molecular Formula | C13H8BrFN2O4 |
| Molecular Weight | 355.12 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
CATO manufactures 5-Bromo-2-(2,6-dioxopiperidin-3-yl)-4-fluoroisoindoline-1,3-dione under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
5-Bromo-2-(2,6-dioxopiperidin-3-yl)-4-fluoroisoindoline-1,3-dione (CAS 2740657-28-5), molecular formula C13H8BrFN2O4 and molecular weight 355.12 g/mol, is a CATO reference standard with documented purity and traceability.
The molecular framework of 5-Bromo-2-(2,6-dioxopiperidin-3-yl)-4-fluoroisoindoline-1,3-dione (C13H8BrFN2O4) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine/bromine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
Physical & Chemical Properties
| Molecular Formula | C13H8BrFN2O4 |
| Molecular Weight | 355.12 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 10.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2002 |
| Halogen Content | F/Br-containing |
| Nitrogen Atoms | 2 |
Related Bromo Standards
- 4-Bromo-2-(2,6-dioxopiperidin-3-yl)-5-fluoroisoindoline-1,3-dione (CAS 2851889-86-4)
- 4-Bromo-2-(2,6-dioxopiperidin-3-yl)-7-fluoroisoindoline-1,3-dione (CAS 2740657-30-9)
- 5-Bromo-2-(2,6-dioxopiperidin-3-yl)-6-fluoroisoindoline-1,3-dione (CAS 2803445-69-2)
- Ethyl 2-bromo-3-oxo-3-[4-(trifluoromethoxy)phenyl]propanoate (CAS 887267-61-0)
- 5-((4-Bromo-3,5-bis(difluoromethyl)-1H-pyrazol-1-yl)methyl)furan-2-carbaldehyde (CAS 1006320-27-9)
- Ethyl 6-bromo-8-fluoro-2-(trifluoromethyl)imidazo[1,2-a]pyridine-3-carboxylate (CAS 2379918-57-5)
- N-(5-bromo-2-methoxybenzyl)-4-fluoro-3-nitroaniline (CAS 306730-60-9)
- 2-(3-Bromo-5-isobutoxyphenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane (CAS 1218789-48-0)
Recommended Standards
- 6-Bromonaphthalen-2-yl trifluoromethanesulfonate (CAS 151600-02-1)
- Methyl 5-(2,6-dichloro-4-(trifluoromethyl)phenoxy)-1H-pyrazole-3-carboxylate (CAS 452098-09-8)
- 2,4-Diamino-6-((4-iodophenyl)amino)pyrimidine-5-carbaldehyde (CAS 16597-44-7)
- 1-Hydroxy-4-((4-methoxyphenyl)thio)anthracene-9,10-dione (CAS 16673-01-1)
- tert-Butyl-N-[4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl]-carbamate 4-boc-aminophenylboronic acid, pinacol ester 4-(Boc-amino)benzeneboronic acid pinacol ester (4-boc-aminophenyl)boronic acid, pinacol ester t-butyl-n-[4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl]carbamate 4-(tert-Butoxycarbonylamino)phenylboronic acid pinacol ester tert-butyl-n-[4-(4,4,5,5-tetramethyl-1,2,3-dioxaborolan-2-yl)phenyl]carbamate tert-butyl 4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenylcarbamate 4-(n-boc-amino)phenylboronic acid pinacol ester tert-butyl-n-[4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl]carbamate 4-butoxycarbonylaminophenylboronic acid, pinacol ester 4-tert-butoxycarbonylaminophenylboronic acid, pinacol 4-(boc-amino)phenylboronic acid pinacol cyclic ester 4-(tert-butoxycarbonyl)aminophenylboronic acid, pinacol ester t-butyl n-[4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolane-2-yl)phenyl]carbamate (4-Boc-aminophenyl)boronic acid pinacol ester 330793-01-6 (CAS 330793-01-6)
- 4-Hydroxy-6,7-dimethoxyquinoline-3-carbonitrile (CAS 50845-31-3)
- 2-(2-Naphthamido)-6-methyl-4,5,6,7-tetrahydrothieno[2,3-c]pyridine-3-carboxamide hydrochloride (CAS 1177815-02-9)
- MK-2894 sodium salt, >98% (HPLC) (CAS 1006036-88-9)
- 2-{2-[(2-Methoxybenzyl)oxy]ethyl}piperidinehydrochloride (CAS 1220018-68-7)
- Cinitapride Impurity 36 (CAS 907969-40-8)
- 2-((5-Methyl-2-phenyl-1H-indol-3-yl)amino)thiazol-4(5H)-one (CAS 126193-48-4)
- 5-Fluoro-3-((4-fluorophenyl)imino)indolin-2-one (CAS 75564-89-5)
- 5-(6-Chloropyridin-3-yl)-3-(p-tolyl)-1,2,4-oxadiazole (CAS 303145-18-8)
- Insulin degludec (CAS 844439-96-9)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com