Salmeterol Impurity 9 CAS 27475-14-5
| CAS No. | 27475-14-5 |
| Molecular Formula | C17H15BrO4 |
| Molecular Weight | 363.20 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 363.20 g/mol gives Salmeterol Impurity 9 distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
CATO supplies Salmeterol Impurity 9 (CAS 27475-14-5), a pharmacopoeial impurity reference standard (molecular formula C17H15BrO4, MW 363.20 g/mol) used for the identification and quantification of trace impurities in APIs.
Owing to a flavonoid core, a hydroxyl group, an ether linkage, bromine substitution, Salmeterol Impurity 9 is typically pale yellow to yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 363.20 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
As a certified reference material (CRM), Salmeterol Impurity 9 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C17H15BrO4 |
| Molecular Weight | 363.20 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 10.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1964 |
| Halogen Content | Br-containing |
Related Salmeterol Standards
- Salmeterol Impurity 2 (CAS 160889-18-9)
- Salmeterol Impurity 28 (CAS CATO-C4X-105028)
- Salmeterol Impurity N1 (CAS 97664-55-6)
- Salmeterol Impurity 12 (CAS 108928-82-1)
- Salmeterol EP Impurity B (CAS 94749-02-7)
- Salmeterol Impurity 29 (CAS CATO-C4X-105029)
- Salmeterol EP Impurity F (CAS 1391054-40-2)
- Salmeterol Impurity 17 (CAS 94749-00-5)
Recommended Standards
- N6-[(3,4-Dichlorophenyl)methyl]-N6-nitroso-2,4,6-quinazolinetriamine (CAS 22316-71-8)
- 4-(4-Bromophenyl)-4-oxo-2-{[(pyridin-3-yl)methyl]amino}butanoic acid (CAS 1042701-72-3)
- Methyl2-(4-benzyloxy-3-bromo-5-formyl-phenyl)acetate (CAS 583031-89-4)
- 2-Bromo-N-{3-[(2-phenoxyacetyl)amino]-phenyl}acetamide (CAS 1138443-07-8)
- Sodium Valproate Impurity 15 (CAS 2163-48-6)
- N-Nitroso Nemonoxacin impurity 107 (CAS CATO-C4X-3128107)
- LCZ-696 Impurity 19(R,R) (CAS 1012341-56-8)
- 2-Chloro-5-iodo-N-methoxy-N-methylbenzamide (CAS 959909-89-8)
- Suvorexant impurity 27 (CAS CATO-C4X-181227)
- N-(2,6-Diphenylpyrimidin-4-yl)cyclobutanecarboxamide (CAS 820961-51-1)
- 2-(tert-Butyl)phenyl carbonochloridate (CAS 203984-34-3)
- 3-(5-Bromo-2-fluorophenyl)isoxazole-5-carboxylic acid (CAS 1126636-69-8)
- 4-(((2-Aminoethyl)(methyl)amino)methyl)benzonitrile (CAS 1250429-03-8)
- Hippocampal Cholinergic Neurostimulating Peptide (CAS 140158-49-2)
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