Parecoxib Impurity 24 CAS 2749361-92-8
| CAS No. | 2749361-92-8 |
| Molecular Formula | C17H15NO4S |
| Molecular Weight | 329.37 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
The molecular framework of Parecoxib Impurity 24 (C17H15NO4S) is characterized by a flavonoid core, an amide group, a sulfone group, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
As a process- or degradation-related impurity, Parecoxib Impurity 24 (CAS 2749361-92-8, C17H15NO4S) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
As a certified reference material (CRM), Parecoxib Impurity 24 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C17H15NO4S |
| Molecular Weight | 329.37 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 11.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2002 |
| Nitrogen Atoms | 1 |
| Sulfur Atoms | 1 |
Related Parecoxib Standards
- Parecoxib sodium Impurity 7 (CAS 501093-49-8)
- Parecoxib Impurity 23 (CAS 509074-26-4)
- Parecoxib (CAS 1709956-95-5)
- Parecoxib Impurity 30 (CAS 1373038-57-3)
- Parecoxib Impurity 31 (CAS CATO-C4X-159131)
- Parecoxib Impurity 25 (CAS 1884279-18-8)
- Parecoxib Impurity 59 (CAS CATO-C4X-159159)
- Parecoxib Impurity 33 (CAS CATO-C4X-159133)
Recommended Standards
- Raltitrexed Impurity 34 (CAS CATO-C4X-138634)
- Bimatoprost Impurity 11 (CAS CATO-C4X-196411)
- Raltitrexed Impurity 14 (CAS CATO-C4X-138614)
- Paroxetine (CAS 61869-08-7)
- Clofarabine Impurity 13 (CAS 1904-98-9)
- Vildagliptin Impurity 105 (CAS CATO-C4X-1100105)
- Tadalafil Impurity N98 (CAS 1795790-92-9)
- 2-chloro-1-{4-[(4-methylphenyl)carbonyl]piperazin-1-yl}ethan-1-one (CAS 693790-62-4)
- 1-(Benzyloxy)-3-isocyanobenzene (CAS 1353562-25-0)
- 5-Acetoxy-2-methylbenzoic acid (CAS 24042-23-7)
- 2-[(2-methylfuran-3-yl)formamido]acetic acid (CAS 926226-44-0)
- 3-Pyridin-3-yl-2H-1,2,4-oxadiazol-5-one (CAS 1198-99-8)
- N-Isopropylpyrimidin-2-amine (CAS 4214-72-6)
- Smac-N7 Peptide (CAS 401913-57-3)
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