rel-3,4-Difluoropyrrolidine-1-sulfonyl chloride CAS 2754410-05-2
| CAS No. | 2754410-05-2 |
| Molecular Formula | C4H6ClF2NO2S |
| Molecular Weight | 205.61 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
As a certified reference material (CRM), rel-3,4-Difluoropyrrolidine-1-sulfonyl chloride meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
rel-3,4-Difluoropyrrolidine-1-sulfonyl chloride (CAS 2754410-05-2), molecular formula C4H6ClF2NO2S and molecular weight 205.61 g/mol, is a CATO reference standard with documented purity and traceability.
The molecular framework of rel-3,4-Difluoropyrrolidine-1-sulfonyl chloride (C4H6ClF2NO2S) is characterized by an amide group, a sulfone group, a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
Physical & Chemical Properties
| Molecular Formula | C4H6ClF2NO2S |
| Molecular Weight | 205.61 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 1.0 |
| CAS Registry Year (est.) | 2002 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 1 |
| Sulfur Atoms | 1 |
Related rel Standards
- 3,3-Difluoropyrrolidine-1-sulfonyl chloride (CAS 1187160-31-1)
- 1-Boc-3,3-difluoropyrrolidine (CAS 195447-25-7)
- 1-Acetyl-4,4-difluoropyrrolidine-3-carboxylic acid (CAS 2144393-04-2)
- 3,3-Difluoropyrrolidine-1-sulfonamide (CAS 924307-83-5)
- 1-Benzyl-3,3-difluoropyrrolidine-2,5-dione (CAS 862416-33-9)
- Ethyl 4,4-difluoropyrrolidine-3-carboxylate (CAS 1258650-97-3)
- Ethyl 3,3-difluoropyrrolidine-2-carboxylate (CAS 779301-37-0)
- Benzyl 3,3-difluoropyrrolidine-1-carboxylate (CAS 163457-22-5)
Recommended Standards
- 6-chloro-7-fluoro-indoline-2,3-dione (CAS 942493-23-4)
- 4-Chloro-2-(methylthio)-5-nitropyrimidine (CAS 1421691-20-4)
- 4-chloro-6-fluoro-2,3-dihydro-1H-indole-2,3-dione (CAS 940054-45-5)
- 1-(5-Chloro-4-nitrothiophen-2-yl)ethan-1-one (CAS 42456-75-7)
- Methyl 6-(ethylamino)-5-nitronicotinate (CAS 954228-35-4)
- Zotepine Impurity12 (CAS 5118-50-3)
- Valsartan Impurity 16 (CAS 195435-23-5)
- (2-Methoxy-5-methylphenyl)(5-methylfuran-2-yl)methanol (CAS 944526-89-0)
- Methyl 3-amino-3-(3-fluoro-4-methoxyphenyl)propanoate (CAS 1425353-85-0)
- 4-(Dimethylamino)-2,3,5-trifluorobenzoic acid (CAS 1309602-70-7)
- Iopamidol Impurity 35 (CAS CATO-C4X-145035)
- 1-(2-Methoxyphenyl)-3-(2-methoxypyrimidin-5-yl)urea (CAS 1396870-40-8)
- 1-(5-Methyl-1-methyl-1h-indol-3-yl)-ethanone (CAS 116176-90-0)
- Tau Peptide (277-291) trifluoroacetate salt (CAS 330456-40-1)
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