tert-Butyl 8-fluoro-1-hydroxy-3,4-dihydroisoquinoline-2(1H)-carboxylate CAS 2757409-65-5

Purity 97%+In StockPharmaceutical Standards
CAS No.2757409-65-5
Molecular FormulaC14H18FNO3
Molecular Weight267.30 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

tert-Butyl 8-fluoro-1-hydroxy-3,4-dihydroisoquinoline-2(1H)-carboxylate CAS 2757409-65-5 chemical structure

Description

Compared with other compounds in its class, the molecular weight of 267.30 g/mol gives tert-Butyl 8-fluoro-1-hydroxy-3,4-dihydroisoquinoline-2(1H)-carboxylate distinctive chromatographic separation conditions and mass-spectrometry parameter settings.

CATO supplies tert-Butyl 8-fluoro-1-hydroxy-3,4-dihydroisoquinoline-2(1H)-carboxylate (CAS 2757409-65-5), a certified reference material (molecular formula C14H18FNO3, MW 267.30 g/mol) for analytical method development and quality control.

Owing to a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine substitution, tert-Butyl 8-fluoro-1-hydroxy-3,4-dihydroisoquinoline-2(1H)-carboxylate is typically off-white to pale yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 267.30 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

As a certified reference material (CRM), tert-Butyl 8-fluoro-1-hydroxy-3,4-dihydroisoquinoline-2(1H)-carboxylate meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.

Physical & Chemical Properties

Molecular FormulaC14H18FNO3
Molecular Weight267.30 g/mol
AppearanceOff-white to pale yellow crystalline powder. (slight halide-like odor)
Purity97%+
StorageStore at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation
Solubility (reference)Soluble in chloroform, dichloromethane, ethyl acetate, DMSO
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions
Degree of Unsaturation (DBE)6.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)2002
Halogen ContentF-containing
Nitrogen Atoms1

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