bis(2-Chloroethyl)phosphoramidic Acid CAS 27578-83-2
| CAS No. | 27578-83-2 |
| Molecular Formula | C4H10Cl2NO3P |
| Molecular Weight | 222.01 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
CATO supplies bis(2-Chloroethyl)phosphoramidic Acid (CAS 27578-83-2), a certified reference material (molecular formula C4H10Cl2NO3P, MW 222.01 g/mol) for analytical method development and quality control.
The molecular framework of bis(2-Chloroethyl)phosphoramidic Acid (C4H10Cl2NO3P) is characterized by an amide group, a phosphonate group, a carboxylic acid group, a hydroxyl group, an ether linkage, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C4H10Cl2NO3P |
| Molecular Weight | 222.01 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO, water |
| Stability | Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | -0.5 |
| CAS Registry Year (est.) | 1964 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 1 |
Related bis Standards
- 2-(1-Chloroethyl)-1-cyclopropyl-1H-imidazo[4,5-c]pyridine (CAS 1437456-36-4)
- 3-(2-Chloroethyl)-7-methylquinolin-2-ol (CAS 73863-55-5)
- 2-Chloroethyl (4-methyl-1,2,3-thiadiazol-5-yl)carbamate (CAS 343373-90-0)
- 1-((2-Chloroethyl)sulfonyl)-4-fluorobenzene (CAS 33330-46-0)
- 5-(1-chloroethyl)-3-(2-methylphenyl)-1,2,4-oxadiazole (CAS 1040053-53-9)
- 2-(1-Chloroethyl)-5-(3-methylphenyl)-1,3,4-oxadiazole (CAS 847837-39-2)
- 2-(2-Chloroethyl)-6-methoxyquinazoline (CAS 2006277-23-0)
- 3-(2-Chloroethyl)-2-methylquinazolin-4(3H)-one (CAS 59760-87-1)
Recommended Standards
- (E)-4,4,5,5-Tetramethyl-2-(3,3,3-trifluoroprop-1-en-1-yl)-1,3,2-dioxaborolane (CAS 2130860-50-1)
- 352525-91-8 C9H8BF3O2 V5429 trans-2-[4-(Trifluoromethyl)phenyl]vinylboronic acid (CAS 352525-91-8)
- (5-(3-Oxopiperazin-1-yl)pyrimidin-2-yl)boronic acid (CAS 1598437-87-6)
- 2,4-Dichloro-5-(trifluoromethyl)thiazole (CAS 105315-48-8)
- 1-[(2,6-Difluorophenyl)methyl]-3-nitro-1h-pyrazole (CAS 1240568-19-7)
- 2,2-Dimethyl-3-phenylcyclopropane-1-carboxylic acid (CAS 50672-13-4)
- 6-Methyl-1H-pyrazolo[3,4-b]pyridin-3-ol (CAS 757142-59-9)
- 5-Phenyl-3-(trifluoromethyl)-2-pyridinecarboxylic acid (CAS 1211578-17-4)
- 2-Hydroxydibenzofuran (CAS 86-77-1)
- QR6QV3EC23 621-29-4 Benzene, 1-isocyanato-3-methyl- m-Tolyl isocyanate AI3-28254 EINECS 210-676-0 EC 210-676-0 UNII-QR6QV3EC23 (CAS 621-29-4)
- Landiolol Impurity 35 (CAS CATO-C4X-262135)
- Diploicin (CAS 527-93-5)
- 4-Chloro-6-(chloromethyl)-1,3-dioxaindane (CAS 885531-04-4)
- Fibronectin Adhesion-Promoting Peptide (CAS 125720-21-0)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com