1-(6-Bromo-5-fluoro-1-methyl-1H-indazol-3-yl)dihydropyrimidine-2,4(1H,3H)-dione CAS 2760850-50-6
| CAS No. | 2760850-50-6 |
| Molecular Formula | C12H10BrFN4O2 |
| Molecular Weight | 341.14 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The molecular framework of 1-(6-Bromo-5-fluoro-1-methyl-1H-indazol-3-yl)dihydropyrimidine-2,4(1H,3H)-dione (C12H10BrFN4O2) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine/bromine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
1-(6-Bromo-5-fluoro-1-methyl-1H-indazol-3-yl)dihydropyrimidine-2,4(1H,3H)-dione (CAS 2760850-50-6), molecular formula C12H10BrFN4O2 and molecular weight 341.14 g/mol, is a CATO reference standard with documented purity and traceability.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
CATO manufactures 1-(6-Bromo-5-fluoro-1-methyl-1H-indazol-3-yl)dihydropyrimidine-2,4(1H,3H)-dione under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C12H10BrFN4O2 |
| Molecular Weight | 341.14 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 9.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2003 |
| Halogen Content | F/Br-containing |
| Nitrogen Atoms | 4 |
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Recommended Standards
- (2S,4R)-1-(tert-Butoxycarbonyl)-4-iodopyrrolidine-2-carboxylic acid (CAS 1932212-37-7)
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- 5-Ethyl-N-(2-iodophenyl)furan-2-carboxamide (CAS 1209200-72-5)
- 2,2«-dichloro-4,4«-dinitroÂbibenzÂyl (CAS 105222-71-7)
- 5-methoxy-1,2,4-thiadiazol-3-amine (CAS 363179-65-1)
- 5-Amino-2-cyclohexyl-1,2,4-thiadiazol-3(2H)-one (CAS 1365939-81-6)
- N-(2,4-Difluorophenyl)-1,1,1-trifluoromethanesulfonamide (CAS 23384-22-7)
- 4-(4-Hydroxyphenyl)-1,3-oxazolidin-2-one (CAS 1059200-23-5)
- 1-(3-iodanylpyridin-1-ium-2-yl)piperazin-4-ium 1-(3-iodo-2-pyridin-1-iumyl)piperazin-4-ium 85386-98-7 A841314 (CAS 85386-98-7)
- 2-(2,4-Dimethoxyphenyl)-1-ethyl-5-oxopyrrolidine-3-carboxylic acid (CAS 887361-21-9)
- (2,6-Dimethylphenyl)(4-methylpyridin-3-yl)methanone (CAS 1187167-79-8)
- 3-[4-(difluoromethoxy)phenyl]-1,2-oxazol-5-amine (CAS 1020955-05-8)
- DBPR108 (CAS 1186426-66-3)
- Tau Peptide (245-274) (Repeat 1 Domain) trifluoroacetate salt (CAS 1428134-39-7)
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