8-Bromo-1-chloro-3-(methoxymethoxy)naphthalene CAS 2766210-86-8
| CAS No. | 2766210-86-8 |
| Molecular Formula | C12H10BrClO2 |
| Molecular Weight | 301.56 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 8-Bromo-1-chloro-3-(methoxymethoxy)naphthalene.
8-Bromo-1-chloro-3-(methoxymethoxy)naphthalene (CAS 2766210-86-8), molecular formula C12H10BrClO2 and molecular weight 301.56 g/mol, is a CATO reference standard with documented purity and traceability.
The molecular framework of 8-Bromo-1-chloro-3-(methoxymethoxy)naphthalene (C12H10BrClO2) is characterized by a carboxylic acid group, a hydroxyl group, an ether linkage, chlorine/bromine substitution, an aromatic ring system. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO manufactures 8-Bromo-1-chloro-3-(methoxymethoxy)naphthalene under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C12H10BrClO2 |
| Molecular Weight | 301.56 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 7.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2003 |
| Halogen Content | Cl/Br-containing |
Related Bromo Standards
- 2-(2-Bromo-5-fluorophenyl)ethanesulfonyl chloride (CAS 1033629-70-7)
- 1-(3-Bromo-4-fluorophenyl)ethane-1-sulfonyl chloride (CAS 1249271-79-1)
- 1-(5-Bromo-7-ethylbenzofuran-2-yl)-2-chloroethanone (CAS 18775-40-1)
- 6-Bromo-1-chloro-2-(methoxymethoxy)naphthalene (CAS 2179038-41-4)
- 5-Bromo-2-chloro-N-cyclobutyl-7H-pyrrolo[2,3-d]pyrimidin-4-amine (CAS 1192711-67-3)
- 2-Bromo-6-(5-chloro-4-isopropyl-4H-1,2,4-triazol-3-yl)pyridine (CAS 2258660-11-4)
- 6-bromo-4-chloro-N,N-dimethyl-1H-indole-2-carboxamide (CAS CATO-C3D-263205)
- 2-(4-Bromo-2-fluorophenyl)-4-chloro-6-methylpyrimidine (CAS 1395552-37-0)
Recommended Standards
- N3-(2,4-dichlorophenyl)-4-chloronicotinamide (CAS 680214-04-4)
- 5-Formyl-2-hydroxy-3-methylbenzoic acid (CAS 6265-16-3)
- 5-Amino-3-methyl-1-(2,4,6-trichlorophenyl)-1H-pyrazole-4-carbonitrile (CAS 362601-75-0)
- 3,6-Dichloro-N-(2-chlorophenyl)picolinamide (CAS 364370-75-2)
- N-((5-bromofuran-2-yl)methyl)-2-(methylsulfonyl)ethan-1-amine (CAS 845658-68-6)
- 2-[(Difluoromethyl)sulfanyl]-1,3-benzoxazole (CAS 943-07-7)
- Tetraacetyl Phytosphingosine (CAS 13018-48-9)
- 1-(4-Methoxyphenyl)naphthalene (CAS 27331-33-5)
- 2-((((9h-Fluoren-9-yl)methoxy)carbonyl)amino)terephthalic acid (CAS 1185298-22-9)
- 6-(3-Methoxyphenyl)picolinimidamide hydrochloride (CAS 1179361-79-5)
- (2-((3,4-Dichlorophenyl)amino)thiazol-5-yl)(phenyl)methanone (CAS 339023-05-1)
- 2-[3-(N-Ethylaminocarbonyl)phenyl]benzoic acid (CAS 1261915-41-6)
- Cis-2,3-difluoro-2,3-dihydrobenzofuran (CAS 66946-74-5)
- Semaglutide Impurity 157 (x TFA Salt) (CAS CATO-C4X-2226157)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com