(3S,4R)-3,4-Difluoro-1-oxaspiro[4.5]decan-8-one CAS 2770345-67-8
| CAS No. | 2770345-67-8 |
| Molecular Formula | C9H12F2O2 |
| Molecular Weight | 190.19 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of (3S,4R)-3,4-Difluoro-1-oxaspiro[4.5]decan-8-one is closely related to a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
(3S,4R)-3,4-Difluoro-1-oxaspiro[4.5]decan-8-one (CAS 2770345-67-8) is a high-purity analytical reference standard with the molecular formula C9H12F2O2 and a molecular weight of 190.19 g/mol.
The molecular framework of (3S,4R)-3,4-Difluoro-1-oxaspiro[4.5]decan-8-one (C9H12F2O2) is characterized by a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine substitution. In reversed-phase chromatography, its retention is governed primarily by the polarity and ionization state of its functional groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
As a certified reference material (CRM), (3S,4R)-3,4-Difluoro-1-oxaspiro[4.5]decan-8-one meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C9H12F2O2 |
| Molecular Weight | 190.19 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 3.0 |
| UV Absorption | UV-absorbing |
| CAS Registry Year (est.) | 2003 |
| Halogen Content | F-containing |
Recommended Standards
- (3R,4R)-3,4-Difluoro-1-oxaspiro[4.5]decan-8-one (CAS 2770345-68-9)
- (5S,6S)-5,6-Dimethoxy-5,6-dimethyl-1,4-dioxan-2-one (CAS 371160-92-8)
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