5-Fluoro-8-((triisopropylsilyl)ethynyl)naphthalene-1,3-diol CAS 2771460-06-9
| CAS No. | 2771460-06-9 |
| Molecular Formula | C21H27FO2Si |
| Molecular Weight | 358.52 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of 5-Fluoro-8-((triisopropylsilyl)ethynyl)naphthalene-1,3-diol is closely related to a steroid core, a hydroxyl group, an ether linkage, fluorine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
5-Fluoro-8-((triisopropylsilyl)ethynyl)naphthalene-1,3-diol (CAS 2771460-06-9) is a high-purity analytical reference standard with the molecular formula C21H27FO2Si and a molecular weight of 358.52 g/mol.
Based on its molecular formula C21H27FO2Si, 5-Fluoro-8-((triisopropylsilyl)ethynyl)naphthalene-1,3-diol contains a steroid core, a hydroxyl group, an ether linkage, fluorine substitution; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 358.52 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO manufactures 5-Fluoro-8-((triisopropylsilyl)ethynyl)naphthalene-1,3-diol under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C21H27FO2Si |
| Molecular Weight | 358.52 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2003 |
| Halogen Content | F-containing |
Related Fluoro Standards
- 2-Fluoro-8-((triisopropylsilyl)ethynyl)naphthalene-1,3-diol (CAS 2791272-29-0)
- 7-Fluoro-8-((triisopropylsilyl)ethynyl)naphthalene-1,3-diol (CAS 2621932-34-9)
- 1-Fluoro-4-{[(4-{[(4-fluorophenyl)sulfanyl]methyl}phenyl)methyl]sulfanyl}benzene (CAS 478258-28-5)
- 2-Fluoro-N-((4-(2-methoxyphenyl)-5-thioxo-4,5-dihydro-1H-1,2,4-triazol-3-yl)methyl)benzamide (CAS 391886-35-4)
- 2-Fluoro-[1,1'-biphenyl]-4-yl 4-methoxybenzene-1-sulfonate (CAS 477857-16-2)
- 2-[4-(3-Fluoro-4-methoxyphenyl)-5-methylpyrimidin-2-yl]-4-(2-hydroxyethyl)-5-methyl-2,3-dihydro-1H-pyrazol-3-one (CAS 866133-80-4)
- N-(4-fluoro-3-nitrophenyl)-2-(4-phenylpiperazin-1-yl)acetamide (CAS 720667-97-0)
- 3-(2-Fluoro-4-nitrophenoxy)-N-phenylthiophene-2-carboxamide (CAS 303152-03-6)
Recommended Standards
- 4-(1,3-Dithiolan-2-yl)phenyl 4-(tert-butyl)benzoate (CAS 261928-90-9)
- N-(4-(4-pentylcyclohexyl)phenyl)morpholine-4-carboxamide (CAS 866131-94-4)
- 2-(4-(tert-Butyl)phenyl)-4-(4-methylpiperidin-1-yl)quinoline (CAS 853310-49-3)
- N-(4-Methylphenyl)-11-(2-methylprop-2-enamido)undecanamide (CAS 866132-11-8)
- 3-(3-Chloropropyl)cyclopent-2-enone (CAS 862367-69-9)
- 4-((1H-pyrazol-1-yl)methoxy)benzoic acid (CAS 1006473-73-9)
- (S)-2-(Aminomethyl)-1,4-dioxane Hydrochloride (CAS 1523541-96-9)
- 3-Amino-5-chloro-4-hydroxybenzenesulfonic acid (CAS 5857-94-3)
- Brimonidine Tartrate (CAS 70359-46-5)
- 3-(3,5-Dimethylphenoxy)-1-methyl-1H-pyrazol-4-amine (CAS 1429418-16-5)
- 4-(2,5-Dimethylphenoxy)butanoic acid (CAS 105401-49-8)
- 5-Ethyl-N-isopropyl-4,5,6,7-tetrahydrobenzo[b]thiophene-2-carboxamide (CAS 941057-77-8)
- Cyanoacetic acid 13C (CAS 67121-16-8)
- Semaglutide Impurity 176 (CAS CATO-C4X-2226176)
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