3-Chloro-5-iodobenzaldehyde CAS 277312-89-7
| CAS No. | 277312-89-7 |
| Molecular Formula | C7H4ClIO |
| Molecular Weight | 266.46 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
3-Chloro-5-iodobenzaldehyde (CAS 277312-89-7) is a high-purity analytical reference standard with the molecular formula C7H4ClIO and a molecular weight of 266.46 g/mol.
The molecular framework of 3-Chloro-5-iodobenzaldehyde (C7H4ClIO) is characterized by a hydroxyl group, an ether linkage, chlorine/iodine substitution, an aromatic ring system. In reversed-phase chromatography, its retention is governed primarily by the polarity and ionization state of its functional groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C7H4ClIO |
| Molecular Weight | 266.46 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at room temperature, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | Cl/I-containing |
Related Chloro Standards
- 5-Chloro-2-iodobenzaldehyde (CAS 1001334-22-0)
- (4-(4-Chloro-2-fluorophenoxy)phenyl)boronic acid (CAS 1256358-57-2)
- 2-Chloro-4-iodobenzaldehyde (CAS 1260810-79-4)
- 2-Chloro-3-iodobenzaldehyde (CAS 1261449-85-7)
- 4-Chloro-2-iodobenzaldehyde (CAS 132901-37-2)
- 3-Chloro-4-iodobenzaldehyde (CAS 148334-14-9)
- 2-Chloro-5-iodobenzaldehyde (CAS 256925-54-9)
- 2-Chloro-6-iodobenzaldehyde (CAS 51738-07-9)
Recommended Standards
- 3-Chloro-2-iodobenzaldehyde (CAS 469912-65-0)
- 4-((3-Hydroxypropyl)thio)-3-(isopropylthio)-4-methylpentan-1-ol (CAS 5921-64-2)
- 3,3'-Disulfanediylbis(hexan-1-ol) (CAS 344738-34-7)
- 4-Chloro-3-iodobenzaldehyde (CAS 276866-90-1)
- 1-(2-Hydroxyethyl)-2,4-dioxo-1,2,3,4-tetrahydropyrimidine-5-carboxamide (CAS 1049130-55-3)
- N1-methyl-N1-((3-methylthiophen-2-yl)methyl)ethane-1,2-diamine (CAS 1250967-24-8)
- N-cyclopentyl-5-methylthiophene-3-carboxamide (CAS 925588-59-6)
- 333435-04-4 4-(5-Chlorocarbonyl-furan-2-yl)-benzoic acid ethyl ester ethyl 4-(5-chlorocarbonyl-2-furyl)benzoate ethyl 4-[5-(chlorocarbonyl)furan-2-yl]benzoate (CAS 333435-04-4)
- 4-Bromo-1-cyclohexyl-1H-pyrazole (CAS 141302-40-1)
- 2-{bicyclo[2.2.1]heptan-2-yl}acetyl chloride (CAS 54057-58-8)
- Ceritinib Impurity 10 (CAS CATO-C4X-1048910)
- 3-Amino-N-(2,6-dichlorophenyl)-6-methyl-5,6,7,8-tetrahydrothieno[2,3-b][1,6]naphthyridine-2-carboxamide (CAS 387831-32-5)
- 3-Chloro-N,N-dipropylbenzamide (CAS 17271-10-2)
- Insulin Degludec Impurity 18 (CAS CATO-C4X-215718)
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