2,2,2-Trifluoroethyl Chloroformate CAS 27746-99-2
| CAS No. | 27746-99-2 |
| Molecular Formula | C3H2ClF3O2 |
| Molecular Weight | 162.49 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
CATO manufactures 2,2,2-Trifluoroethyl Chloroformate under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
CATO supplies 2,2,2-Trifluoroethyl Chloroformate (CAS 27746-99-2), a certified reference material (molecular formula C3H2ClF3O2, MW 162.49 g/mol) for analytical method development and quality control.
Owing to a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution, 2,2,2-Trifluoroethyl Chloroformate is typically white to off-white crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 162.49 g/mol — guide the selection of appropriate sample preparation and analytical techniques. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
Physical & Chemical Properties
| Molecular Formula | C3H2ClF3O2 |
| Molecular Weight | 162.49 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 1.0 |
| CAS Registry Year (est.) | 1964 |
| Halogen Content | F/Cl-containing |
Related Trifluoroethyl Standards
- 3-(2,2,2-Trifluoroethyl)pyridine (CAS 1099598-09-0)
- 3-Methyl-1-(2,2,2-trifluoroethyl)-1H-pyrazole (CAS 123657-17-0)
- 2-[(2,2,2-trifluoroethyl)sulfanyl]ethan-1-ol (CAS 5187-61-1)
- (1,1,2-Trifluoroethyl)benzene (CAS 75600-46-3)
- (2,2,2-Trifluoroethyl)benzene (CAS 21249-93-4)
- 5-(2,2,2-Trifluoroethyl)-1H-pyrazol-3-amine (CAS 1001354-48-8)
- 4-(2,2,2-Trifluoroethyl)-1H-pyrazol-3-amine (CAS 1057259-62-7)
- 1-(2,2,2-Trifluoroethyl)-1h-imidazol-4-amine (CAS 1200606-93-4)
Recommended Standards
- 3-Chlorobenzeneboronic acid 3-chlorophenylboronic acid 3-chloro-phenyl-boronic acid 3-chlorophenyl boronic acid (3-chlorophenyl)boranediol (3-chlorophenyl)boronic acid 3-chlorophenylbornic acid m-Chlorophenylboronic acid 63503-60-6 (CAS 63503-60-6)
- 3-Chloro-2,2,3-trifluoropropanoic acid (CAS 425-97-8)
- 2-Chlorobenzeneboronic acid 2-chlorophenylboronic acid 2-chloro-phenyl-boronic acid 2-chlorophenyl boronic acid (2-chlorophenyl)boranediol 2-chlorophenylbornic acid o-Chlorophenylboronic acid 3900-89-8 (CAS 3900-89-8)
- Dy Standard Solution (CAS 7429-91-6)
- (1-Propyl-1h-pyrazol-3-yl)methanol (CAS 1007489-19-1)
- 4-((Furan-2-ylmethyl)carbamoyl)-1,2,2-trimethylspiro[2.3]Hexane-1-carboxylic acid (CAS 352452-38-1)
- cis-Piceatannol (CAS 106325-86-4)
- 4-Fluoro-2-methoxy-5-methylaniline (CAS 314298-14-1)
- (S)-3-Piperidinemethanol (CAS 144539-77-5)
- 5-bromo-1-(propan-2-yl)-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-1,2,3-triazole (CAS 2364586-27-4)
- 6-Methyl-2-(prop-2-yn-1-ylthio)pyrimidin-4(3H)-one (CAS 88037-20-1)
- 3-Fluoro-4-(trifluoromethyl)picolinonitrile (CAS 1706436-98-7)
- Imidazo[1,5-a]pyridin-5-ylmethanol (CAS 1823953-42-9)
- Autoinducing Peptide I trifluoroacetate salt (CAS 200010-29-3)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com