Loxapine Succinate CAS 27833-64-3
| CAS No. | 27833-64-3 |
| Molecular Formula | C18H18ClN3O |
| Molecular Weight | N/A |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including Loxapine Succinate.
Loxapine Succinate (CAS 27833-64-3), molecular formula C18H18ClN3OC4H6O4 and molecular weight 445.90 g/mol, is a CATO reference standard with documented purity and traceability.
The molecular framework of Loxapine Succinate (C18H18ClN3OC4H6O4) is characterized by a flavonoid core, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
As a certified reference material (CRM), Loxapine Succinate meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C18H18ClN3O C4H6O4 |
| Molecular Weight | 445.90 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 12.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1964 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 3 |
Related Loxapine Standards
Recommended Standards
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- 4-(Aminomethyl)-5-cyano-2-(trifluoromethoxy)benzene-1-sulfonyl chloride (CAS 1807089-48-0)
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- N-(4-Bromobenzyl)-2,2-dimethoxyethylamine (CAS 1036378-89-8)
- N-(Butoxycarbonyl)-3-[[2-[(5R)-3-(4-cyanophenyl)-4,5-dihydro-5-isoxazolyl]acetyl]amino]-,methyl esterL-alanine (CAS 188016-51-5)
- 2-Fluorobenzoyl isocyanate (CAS 62869-34-5)
- Rel-((1S,2S,4S)-bicyclo[2.2.1]hept-5-en-2-yl)methanol (CAS 15507-06-9)
- Liraglutide Impurity 31 (CAS CATO-C4X-199231)
Why CATO?
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