Phenytoin Impurity N15 CAS 2784-27-2
| CAS No. | 2784-27-2 |
| Molecular Formula | C15H12N2O3 |
| Molecular Weight | 268.27 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
CATO supplies Phenytoin Impurity N15 (CAS 2784-27-2), a pharmacopoeial impurity reference standard (molecular formula C15H12N2O3, MW 268.27 g/mol) used for the identification and quantification of trace impurities in APIs.
Phenytoin Impurity N15 (C15H12N2O3) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage. It is notably hygroscopic, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C15H12N2O3 |
| Molecular Weight | 268.27 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 11.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1957 |
| Nitrogen Atoms | 2 |
Related Phenytoin Standards
- Phenytoin Impurity 2 (CAS 21083-47-6)
- Phenytoin EP Impurity F (CAS 51169-17-6)
- Phenytoin Impurity 1 (CAS 5157-13-1)
- Phenytoin EP Impurity E (CAS 6802-95-5)
- Phenytoin Impurity 15 (CAS CATO-C4X-186415)
- Phenytoin-d10 (CAS 65854-97-9)
- Phenytoin Impurity 1 (CAS 61693-07-0)
- Phenytoin Impurity 22 (CAS CATO-C4X-186422)
Recommended Standards
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- N-Boc-3-Methoxy-4-nitroaniline (CAS 877671-39-1)
- tert-Butyl (2-methoxy-5-nitrophenyl)carbamate (CAS 211564-07-7)
- Atrasentan Impurity 178 (CAS 1059052-03-7)
- Moxifloxacin Impurity 23 (CAS 154093-72-8)
- Axitinib Impurity 54 (CAS CATO-C4X-107154)
- 3-Fluoro-5-(trifluoromethoxy)benzamide (CAS 1352999-12-2)
- 2-(Furan-2-ylmethylamino)nicotinonitrile (CAS 945347-58-0)
- 3’,5’-Dichloro-2’-hydroxyacetophenone (CAS 3321-92-4)
- tert-Butyl ((benzyloxy)carbonyl)-D-phenylalaninate (CAS 112924-08-0)
- Regorafenib Impurity 11 (CAS CATO-C4X-104711)
- 4-Amidinopyridine Hydrochloride (CAS 6345-27-3)
- [Tyr0] Fibrinopeptide A, human (CAS 103226-11-5)
Why CATO?
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- 130,000+ catalog items in stock, COA supplied with every batch
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