5-[(2-Chloro-6-fluorophenyl)methylidene]-2,2-dimethyl-1,3-dioxane-4,6-dione CAS 278597-15-2
| CAS No. | 278597-15-2 |
| Molecular Formula | C13H10ClFO4 |
| Molecular Weight | 284.67 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
5-[(2-Chloro-6-fluorophenyl)methylidene]-2,2-dimethyl-1,3-dioxane-4,6-dione (CAS 278597-15-2) is a high-purity analytical reference standard with the molecular formula C13H10ClFO4 and a molecular weight of 284.67 g/mol.
Owing to a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution, an aromatic ring system, 5-[(2-Chloro-6-fluorophenyl)methylidene]-2,2-dimethyl-1,3-dioxane-4,6-dione is typically pale yellow to yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 284.67 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
CATO manufactures 5-[(2-Chloro-6-fluorophenyl)methylidene]-2,2-dimethyl-1,3-dioxane-4,6-dione under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C13H10ClFO4 |
| Molecular Weight | 284.67 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | F/Cl-containing |
Related Chloro Standards
- Methyl 1-((3-chloro-4-fluorophenoxy)methyl)-1h-pyrazole-3-carboxylate (CAS 1001500-21-5)
- 1-((3-Chloro-4-fluorophenoxy)methyl)-1h-pyrazole-3-carbohydrazide (CAS 1004193-94-5)
- 3-[(3-Chloro-4-Methoxyphenyl)Methyl]-5-Fluoro-1H-Pyrimidine-2,4-Dione (CAS 102613-23-0)
- Methyl 4-chloro-1-((3-fluorophenoxy)methyl)-1h-pyrazole-3-carboxylate (CAS 1170483-71-2)
- 1-[(2-chloro-4-fluorophenyl)methyl]-6-oxo-1,4,5,6-tetrahydropyridazine-3-carboxylic acid (CAS 926206-27-1)
- 5-((2-Chloro-4-fluorophenoxy)methyl)furan-2-carbohydrazide (CAS 832737-61-8)
- 5-((2-Chloro-6-fluorobenzyl)oxy)-2-(hydroxymethyl)-4H-pyran-4-one (CAS 866040-48-4)
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Recommended Standards
- Ethyl 1-(3-chloro-4-fluorophenyl)-4-hydroxy-1H-pyrazole-3-carboxylate (CAS 379241-53-9)
- Ethyl 1-amino-7-chloro-6-fluoro-4-oxo-1,4-dihydroquinoline-3-carboxylate (CAS 88569-30-6)
- Methyl 3-(2-chloroacetamido)-5-fluoro-1H-indole-2-carboxylate (CAS 843631-16-3)
- Methyl 5-((2-chloro-4-fluorophenoxy)methyl)furan-2-carboxylate (CAS 438220-96-3)
- [(2,4,6-Trimethyl-phenylcarbamoyl)-methyl]-carbamic acid tert-butyl ester (CAS 1043391-05-4)
- (4-Methoxyphenyl)methanesulfonyl fluoride (CAS 1892495-27-0)
- 6-Chloro-2-(methylthio)-9-β-D-ribofuranosyl-9H-purine (CAS 4105-32-2)
- 5-Bromo-1-(cyanomethyl)-1H-pyrazole-4-carbonitrile (CAS 1823407-59-5)
- 2-Ethylbutanoyl cyanide (CAS 99967-32-5)
- 2-[3-(Benzenesulfonyl)-4-{[3-chloro-5-(trifluoromethyl)pyridin-2-yl]oxy}phenoxy]-3-chloro-5-(trifluoromethyl)pyridine (CAS 338406-80-7)
- 5-Formyl-2-hydroxy-3-methoxybenzonitrile (CAS 73289-80-2)
- 5-Fluoro-N,N-dimethyl-2-(tetramethyl-1,3,2-dioxaborolan-2-yl)benzamide (CAS 2377609-26-0)
- Cefuroxime Impurity 59 (CAS CATO-C4X-124559)
- Semaglutide impurity 75 (CAS CATO-C4X-222675)
Why CATO?
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