7-(piperazin-1-ylmethyl)-5H-pyrimido[2,1-b][1,3]thiazol-5-one CAS 278614-87-2

Purity 97%+In StockPharmaceutical Standards
CAS No.278614-87-2
Molecular FormulaC11H14N4OS
Molecular Weight250.32 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

7-(piperazin-1-ylmethyl)-5H-pyrimido[2,1-b][1,3]thiazol-5-one CAS 278614-87-2 chemical structure

Description

Compared with other compounds in its class, the molecular weight of 250.32 g/mol gives 7-(piperazin-1-ylmethyl)-5H-pyrimido[2,1-b][1,3]thiazol-5-one distinctive chromatographic separation conditions and mass-spectrometry parameter settings.

7-(piperazin-1-ylmethyl)-5H-pyrimido[2,1-b][1,3]thiazol-5-one (CAS 278614-87-2), molecular formula C11H14N4OS and molecular weight 250.32 g/mol, is a CATO reference standard with documented purity and traceability.

The molecular framework of 7-(piperazin-1-ylmethyl)-5H-pyrimido[2,1-b][1,3]thiazol-5-one (C11H14N4OS) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, sulfur-containing functionality, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

As a certified reference material (CRM), 7-(piperazin-1-ylmethyl)-5H-pyrimido[2,1-b][1,3]thiazol-5-one meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.

Physical & Chemical Properties

Molecular FormulaC11H14N4OS
Molecular Weight250.32 g/mol
Purity97%+
StorageStore at 2-8°C, protect from light
Solubility (reference)Soluble in DMSO, DMF, methanol
StabilityLight-sensitive; avoid direct strong light
Degree of Unsaturation (DBE)7.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)2025
Nitrogen Atoms4
Sulfur Atoms1

Related piperazin Standards

Recommended Standards

Why CATO?