7-Bromo-2,4-dichloro-8-fluoro-6-methoxyquinazoline CAS 2788907-22-0
| CAS No. | 2788907-22-0 |
| Molecular Formula | C9H4BrCl2FN2O |
| Molecular Weight | 325.95 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
7-Bromo-2,4-dichloro-8-fluoro-6-methoxyquinazoline (CAS 2788907-22-0), molecular formula C9H4BrCl2FN2O and molecular weight 325.95 g/mol, is a CATO reference standard with documented purity and traceability.
Owing to a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine/chlorine/bromine substitution, 7-Bromo-2,4-dichloro-8-fluoro-6-methoxyquinazoline is typically off-white to pale yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 325.95 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
As a certified reference material (CRM), 7-Bromo-2,4-dichloro-8-fluoro-6-methoxyquinazoline meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C9H4BrCl2FN2O |
| Molecular Weight | 325.95 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 7.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2003 |
| Halogen Content | F/Cl/Br-containing |
| Nitrogen Atoms | 2 |
Related Bromo Standards
- 7-Bromo-4,6-dichloro-8-fluoro-5-methoxyquinazoline (CAS 2823477-69-4)
- 5-Bromo-2-(bromodifluoromethyl)-1H-benzo[d]imidazole (CAS 1353778-39-8)
- Methyl 2-bromo-2-(3-bromo-4-fluorophenyl)acetate (CAS 1566900-03-5)
- Methyl 4-bromo-2-(bromomethyl)-5-fluorobenzoate (CAS 1614234-12-6)
- Methyl 2-bromo-5-(bromomethyl)-4-fluorobenzoate (CAS 1628605-15-1)
- 6-Bromo-5-(bromomethyl)-4-(difluoromethyl)picolinonitrile (CAS 1806048-18-9)
- 2-Bromo-5-(bromomethyl)-3-(difluoromethyl)isonicotinonitrile (CAS 1806048-35-0)
- 6-Bromo-4-(bromomethyl)-5-(difluoromethyl)nicotinonitrile (CAS 1806827-79-1)
Recommended Standards
- Methyl 3,5-dibromo-2,4-dihydroxybenzoate (CAS 885279-78-7)
- 6-Bromo-3-(2-bromoethoxy)-2-nitropyridine (CAS 959992-61-1)
- Methyl 4-(dibromomethyl)-3-fluorobenzoate (CAS 1134777-51-7)
- 5,6-Dibromohexahydro-4,7-epoxyisobenzofuran-1,3-dione (CAS 51371-59-6)
- sodium;(3R)-3-(4-chlorophenyl)-4-hydroxybutanoate (CAS 1346617-22-8)
- (7H-Pyrrolo[2,3-d]pyrimidin-4-yl)methanamine hydrochloride (CAS 1378817-39-0)
- 4-Ethylphenyl acetate (CAS 3245-23-6)
- Methyl 4-bromo-5-(tert-butyl)-1-phenyl-1H-pyrazole-3-carboxylate (CAS 1262865-57-5)
- 2-Amino-3-mercaptopropan-1-ol (CAS 584-01-0)
- 1-(3-(Benzyloxy)pyridin-2-yl)-3-(4-methoxybenzyl)urea (CAS 1023511-68-3)
- 2-(Difluoromethoxy)-5-fluoro-3-(pyridin-4-yl)pyridine (CAS 1214330-48-9)
- 3-Hydroxy-2,3-dimethylbutan-2-yl hydrogen (5-morpholinofuran-2-yl)boronate (CAS 2223029-57-8)
- 1-(Furan-2-yl)-3-(thiophen-2-yl)propane-1,3-dione (CAS 32267-05-3)
- Glucagon Monohydrochloride (CAS 28270-04-4)
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