((2S,7aR)-2-((tert-Butyldiphenylsilyl)oxy)tetrahydro-1H-pyrrolizin-7a(5H)-yl)methanol CAS 2791271-70-8
| CAS No. | 2791271-70-8 |
| Molecular Formula | C24H33NO2Si |
| Molecular Weight | 395.61 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
((2S,7aR)-2-((tert-Butyldiphenylsilyl)oxy)tetrahydro-1H-pyrrolizin-7a(5H)-yl)methanol (CAS 2791271-70-8), molecular formula C24H33NO2Si and molecular weight 395.61 g/mol, is a CATO reference standard with documented purity and traceability.
((2S,7aR)-2-((tert-Butyldiphenylsilyl)oxy)tetrahydro-1H-pyrrolizin-7a(5H)-yl)methanol (C24H33NO2Si) contains a steroid core, an amide group, a hydroxyl group, an ether linkage. Its high carbon-to-hydrogen ratio confers good lipid solubility, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), ((2S,7aR)-2-((tert-Butyldiphenylsilyl)oxy)tetrahydro-1H-pyrrolizin-7a(5H)-yl)methanol meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C24H33NO2Si |
| Molecular Weight | 395.61 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 9.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2003 |
| Nitrogen Atoms | 1 |
Recommended Standards
- ((2R,7aS)-2-((tert-Butyldiphenylsilyl)oxy)tetrahydro-1H-pyrrolizin-7a(5H)-yl)methanol (CAS 2791271-76-4)
- 3-(4-Bromophenyl)-1-(3-chloro-4-fluorophenyl)-1H-pyrazole-5-carboxylic acid (CAS 618102-64-0)
- Methyl (2R,3S)-2-Benzylamino-2-(t-butyldimethylsilyloxymethyl)-3-hydroxy-4-methylpentanoate (CAS 145451-92-9)
- O-(12-((tert-Butoxycarbonyl)amino)dodecyl) methanesulfonothioate (CAS 1346598-35-3)
- 4-Bromo-2,3,5,6-tetramethylbenzoic acid (CAS 3360-64-3)
- Quetiapine DBTP N-Methyl Impurity (CAS 1977-09-9)
- N-(tert-Butyloxy)carbonyl Anthranilic Acid- (CAS 176850-22-9)
- Z-His-Phe-Trp-OEt (CAS 10119-01-4)
- 1-(1-Phenyl-1H-pyrazol-3-yl)ethan-1-one (CAS 91137-73-4)
- Ethyl 2-(7-ethyl-6-oxohexahydro-1H-pyrazino[1,2-c]pyrimidin-2(6H)-yl)acetate (CAS 56926-08-0)
- 3-[4-(Benzyloxy)phenyl]thiophene (CAS 893738-95-9)
- 4-methyl-5-[(4-methylphenyl)methyl]-1,3-thiazol-2-amine hydrobromide (CAS 1181458-74-1)
- 5-Bromo-N-ethyl-2-methylaniline (CAS 1157928-89-6)
- Exenatide (CAS 141758-74-9)
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