1,1-dimethyl-3-[3-(1,1,2,2-tetrafluoroethoxy)phenyl]urea CAS 27954-37-6
| CAS No. | 27954-37-6 |
| Molecular Formula | C11H18F4N2O2 |
| Molecular Weight | 286.27 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 1,1-dimethyl-3-[3-(1,1,2,2-tetrafluoroethoxy)phenyl]urea.
1,1-dimethyl-3-[3-(1,1,2,2-tetrafluoroethoxy)phenyl]urea (CAS 27954-37-6), molecular formula C11H18F4N2O2 and molecular weight 286.27 g/mol, is a CATO reference standard with documented purity and traceability.
1,1-dimethyl-3-[3-(1,1,2,2-tetrafluoroethoxy)phenyl]urea (C11H18F4N2O2) contains an amide group, a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine substitution. It is notably hygroscopic, halogen substitution raises its density and boiling point, its high carbon-to-hydrogen ratio confers good lipid solubility, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C11H18F4N2O2 |
| Molecular Weight | 286.27 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 2.0 |
| CAS Registry Year (est.) | 1964 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 2 |
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Recommended Standards
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- Tert-butyl 6'-chloro-1',4'-dihydro-2'h-spiro[piperidine-4,3'-quinoline]-1-carboxylate (CAS 2197063-07-1)
- 1-((3,5-Dimethylphenoxy)methyl)-1h-pyrazole-3-carbohydrazide (CAS 1004194-13-1)
- Sodium 4-hydroxy-3-(trifluoromethoxy)benzoate (CAS 1806300-17-3)
- 1-(3-(4-Aminophenyl)-4,5-dihydro-1H-pyrazol-1-yl)-2-(3,4-dimethoxyphenyl)ethanone (CAS 1076690-12-4)
- 6-(4-Cyclohexylphenyl)-4-(1-methyl-1H-indol-3-yl)-2,3,4,5-tetrahydropyridazin-3-one (CAS 946385-95-1)
- 2-(7-Methoxy-4,8-dimethyl-2-oxo-2H-chromen-3-yl)acetic acid (CAS 701283-97-8)
- 3-Chloro-N-(m-tolyl)propanamide (CAS 19352-22-8)
- 2-Bromo-3-(3,5-dimethyl-4-methoxyphenyl)-1-propene (CAS 951893-08-6)
- Tirzepatide Impurity 17 (CAS CATO-C4X-324017)
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