6-bromopyridin-2-ol CAS 27992-32-1
| CAS No. | 27992-32-1 |
| Molecular Formula | C5H4BrNO |
| Molecular Weight | 174.00 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
6-bromopyridin-2-ol (CAS 27992-32-1) is a high-purity analytical reference standard with the molecular formula C5H4BrNO and a molecular weight of 174.00 g/mol.
The molecular framework of 6-bromopyridin-2-ol (C5H4BrNO) is characterized by an amide group, a hydroxyl group, an ether linkage, bromine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
As a certified reference material (CRM), 6-bromopyridin-2-ol meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C5H4BrNO |
| Molecular Weight | 174.00 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| CAS Registry Year (est.) | 1964 |
| Halogen Content | Br-containing |
| Nitrogen Atoms | 1 |
Related bromopyridin Standards
- 3-Bromopyridin-4(1H)-one (CAS 70149-39-2)
- 5-Bromopyridin-2(1H)-one (CAS 49843-23-4)
- 2-bromopyridin-4-amine (CAS 7598-35-8)
- 4-Bromopyridin-2(1H)-One (CAS 947407-84-3)
- (6-Bromopyridin-2-yl)methanamine (CAS 188637-63-0)
- (3-Bromopyridin-2-yl)hydrazine (CAS 54231-41-3)
- 2-(4-Bromopyridin-3-yl)acetonitrile (CAS 1211539-87-5)
- 2-(3-Bromopyridin-2-yl)acetonitrile (CAS 122851-60-9)
Recommended Standards
- 6-Bromopyrazin-2-amine (CAS 54237-53-5)
- 5-Bromopyrimidin-2-amine (CAS 7752-82-1)
- 6-Bromo-3-pyridinol (CAS 55717-45-8)
- Upadacitinib Impurity 164 (CAS CATO-C4X-2405164)
- 1,2-Dicyclohexylethane (CAS 3321-50-4)
- 2,5-Dimethoxypyridin-3-amine (CAS 1211595-19-5)
- 2-(Cyclohexylthio)-5-(1-tosylpyrrolidin-2-yl)pyridine (CAS 1352512-86-7)
- 2-Amino-4-hydroxy-6-isopropylprimidine 2-amino-6-isopropylpyrimidin-4-ol 73576-32-6 (CAS 73576-32-6)
- Methamidophos D6 (dimethyl D6) (CAS 1219799-41-3)
- (2S,3R)-3-amino-4-(diphenylphosphanyl)butan-2-ol hydrochloride (CAS 1264520-20-8)
- N-(3-methoxypyrazin-2-yl)-n-((4-nitrophenyl)sulfonyl)acetamide (CAS 96097-52-8)
- Methyl 7-methoxybenzo[b]thiophene-2-carboxylate (CAS 88791-17-7)
- 3-Hydroxy-2,3-dimethylbutan-2-yl hydrogen (4-(prop-2-yn-1-yloxy)phenyl)boronate (CAS 2280980-72-3)
- Peptide 6A (H-6905.0005) (CAS 73549-32-3)
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