[(4-fluorophenyl)amino]thiourea CAS 280133-47-3
| CAS No. | 280133-47-3 |
| Molecular Formula | C7H8FN3S |
| Molecular Weight | 185.22 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
[(4-fluorophenyl)amino]thiourea (CAS 280133-47-3) is a high-purity analytical reference standard with the molecular formula C7H8FN3S and a molecular weight of 185.22 g/mol.
The molecular framework of [(4-fluorophenyl)amino]thiourea (C7H8FN3S) is characterized by a nitrile group, sulfur-containing functionality, fluorine substitution, an aromatic ring system. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
As a certified reference material (CRM), [(4-fluorophenyl)amino]thiourea meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C7H8FN3S |
| Molecular Weight | 185.22 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 3 |
| Sulfur Atoms | 1 |
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- 2-{2-[(tert-Butoxy)carbonyl]-2-azaspiro[3.3]heptan-6-yl}acetic acid (CAS 1251002-39-7)
- [2-(2,2-difluoroethoxy)pyridin-3-yl]methanamine (CAS 1423033-53-7)
- 6-Chloro-N-(2-hydroxyethyl)pyridazine-3-carboxamide (CAS 202135-67-9)
- 1-[3-Chloro-5-(trifluoromethyl)pyridin-2-yl]-N'-[(1E)-(4-methoxyphenyl)methylidene]piperidine-4-carbohydrazide (CAS 338761-38-9)
- Insulin Degludec Impurity 9 (CAS CATO-C4X-21579)
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