3,5-Dihydroxy-4-methylbenzoic Acid CAS 28026-96-2
| CAS No. | 28026-96-2 |
| Molecular Formula | C8H8O4 |
| Molecular Weight | 168.15 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
3,5-Dihydroxy-4-methylbenzoic Acid (CAS 28026-96-2), molecular formula C8H8O4 and molecular weight 168.15 g/mol, is a CATO reference standard with documented purity and traceability.
3,5-Dihydroxy-4-methylbenzoic Acid (C8H8O4) contains a carboxylic acid group, a hydroxyl group, an ether linkage, an aromatic ring system. It is notably hygroscopic, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), 3,5-Dihydroxy-4-methylbenzoic Acid meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C8H8O4 |
| Molecular Weight | 168.15 g/mol |
| Appearance | Off-white to pale yellow crystalline powder |
| Purity | >95% |
| Storage | Store at 2-8°C, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1965 |
Related Dihydroxy Standards
- 4,5-Dihydroxy-2-methylbenzoic acid (CAS 127531-40-2)
- 3,4-Dihydroxy-2-methylbenzoic acid (CAS 168899-47-6)
- 2,2-Dihydroxy-1-(4-hydroxyphenyl)ethanone (CAS 197447-05-5)
- 2,3-Dihydroxy-4-methylbenzoic acid (CAS 3929-89-3)
- 2,3-Dihydroxy-5-methoxybenzaldehyde (CAS 73275-94-2)
- 2,3-Dihydroxy-5-methylbenzoic acid (CAS 6049-93-0)
- 2,4-Dihydroxy-3-methoxybenzaldehyde (CAS 58922-29-5)
- 2,4-Dihydroxy-3-methylbenzoic acid (CAS 4707-49-7)
Recommended Standards
- Norcantharidin (CAS 5442-12-6)
- 2-Methoxy-5-nitroaniline (CAS 99-59-2)
- Homogentisic Acid (CAS 451-13-8)
- 1000520-92-2 (4-Fluoro-3-methylphenyl)acetic acid DTXSID40653458 (CAS 1000520-92-2)
- 2-(Quinazolin-4-yloxy)acetic acid (CAS 842959-64-2)
- Methyl 3-(quinolin-6-yl)propanoate (CAS 1514538-89-6)
- 7-Benzyl-2-phenyl-2,7-diazaspiro[4.5]decan-1-one (CAS 852339-03-8)
- 4-Ethoxyphenyl chloroformate (CAS 37782-55-1)
- 1-(4-Chloro-3-nitrophenyl)pyrrolidine-2,5-dione (CAS 882081-32-5)
- Spermidine Trihydrochloride (CAS 334-50-9)
- (S)-2-(Benzylamino)-3-phenylpropanoic acid (CAS 19461-04-2)
- 2-Acetyl-1-pyrroline, ~10% w/w in Toluene (CAS 85213-22-5)
- 2-(3-(4-Chlorophenyl)pyrazin-2-yl)thiazolidin-4-one (CAS 89442-12-6)
- ([13C6]Leu14)-Glucagon (1-29) (human, rat, porcine) trifluoroacetate salt (CAS 1802078-39-2)
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