4-Hydroxy-8-methoxyquinoline-3-carboxylic acid CAS 28027-18-1
| CAS No. | 28027-18-1 |
| Molecular Formula | C11H9NO4 |
| Molecular Weight | 219.19 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 4-Hydroxy-8-methoxyquinoline-3-carboxylic acid.
4-Hydroxy-8-methoxyquinoline-3-carboxylic acid (CAS 28027-18-1) is a high-purity analytical reference standard with the molecular formula C11H9NO4 and a molecular weight of 219.19 g/mol.
Based on its molecular formula C11H9NO4, 4-Hydroxy-8-methoxyquinoline-3-carboxylic acid contains an amino-acid-derived structure, an amide group, a hydroxyl group, an ether linkage; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 219.19 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
As a certified reference material (CRM), 4-Hydroxy-8-methoxyquinoline-3-carboxylic acid meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C11H9NO4 |
| Molecular Weight | 219.19 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1965 |
| Nitrogen Atoms | 1 |
Related Hydroxy Standards
- 2-(7-Hydroxy-2-oxo-2h-chromen-4-yl)acetamide (CAS 101999-45-5)
- 4-Hydroxy-7-methoxyquinoline-6-carboxylic acid (CAS 1190837-18-3)
- N-(4-hydroxy-2-oxo-2H-chromen-3-yl)acetamide (CAS 13948-45-3)
- Methyl 4-hydroxy-1-oxo-1,2-dihydroisoquinoline-3-carboxylate (CAS 13972-97-9)
- 3-hydroxy-7-methoxyquinoline-4-carboxylic acid (CAS 1487292-95-4)
- 5-Hydroxy-3-phenylisoxazole-4-carboxylic acid (CAS 15969-44-5)
- 2-Hydroxy-8-methoxyquinoline-3-carboxylic acid (CAS 169321-92-0)
- 5-Hydroxy-2-methyl-1-oxo-1,2-dihydroisoquinoline-6-carboxylic acid (CAS 1783406-37-0)
Recommended Standards
- 4-Hydroxy-7-methoxyquinoline-3-carboxylic Acid (CAS 28027-17-0)
- 4-Methyl-3-(4-nitrophenyl)furan-2(5H)-one (CAS 7692-92-4)
- 4-Hydroxy-6-methoxyquinoline-3-carboxylic acid (CAS 28027-16-9)
- 4-Methyl-4-nitroheptanedioic acid (CAS 5437-39-8)
- 4-(2-Fluorobenzoyl)-1H-pyrrole-2-carboxamide (CAS 338976-89-9)
- Methyl 3-((1,3-Dioxoisoindolin-2-Yl)Oxy)-2-Hydroxy-2-Methylpropanoate (CAS 367520-87-4)
- 5-Fluoro-2-methoxy-4-picoline (CAS 884495-11-8)
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