Methyl 2-acetamido-4-bromo-3-fluoro-5-(trifluoromethyl)benzoate CAS 2803279-90-3
| CAS No. | 2803279-90-3 |
| Molecular Formula | C11H8BrF4NO3 |
| Molecular Weight | 358.08 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The molecular framework of Methyl 2-acetamido-4-bromo-3-fluoro-5-(trifluoromethyl)benzoate (C11H8BrF4NO3) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine/bromine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
CATO supplies Methyl 2-acetamido-4-bromo-3-fluoro-5-(trifluoromethyl)benzoate (CAS 2803279-90-3), a certified reference material (molecular formula C11H8BrF4NO3, MW 358.08 g/mol) for analytical method development and quality control.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
As a certified reference material (CRM), Methyl 2-acetamido-4-bromo-3-fluoro-5-(trifluoromethyl)benzoate meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C11H8BrF4NO3 |
| Molecular Weight | 358.08 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2003 |
| Halogen Content | F/Br-containing |
| Nitrogen Atoms | 1 |
Related Methyl Standards
- Ethyl 2-acetamido-6-bromo-7-hydroxybenzo[b]thiophene-3-carboxylate (CAS 113407-93-5)
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- 4-[N-[2-(Acetamido)ethyl]-N-methylamino]-2-carboxy-2-hydroxybenzophenone (CAS 203580-77-2)
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