1-(3,5-Bis(trifluoromethyl)phenyl)-3-((1S,2S)-2-(isoindolin-2-yl)cyclohexyl)thiourea CAS 2803369-96-0
| CAS No. | 2803369-96-0 |
| Molecular Formula | C23H23F6N3S |
| Molecular Weight | 487.50 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of 1-(3,5-Bis(trifluoromethyl)phenyl)-3-((1S,2S)-2-(isoindolin-2-yl)cyclohexyl)thiourea is closely related to a nitrogen-containing heterocyclic scaffold, a nitrile group, sulfur-containing functionality, fluorine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
1-(3,5-Bis(trifluoromethyl)phenyl)-3-((1S,2S)-2-(isoindolin-2-yl)cyclohexyl)thiourea (CAS 2803369-96-0), molecular formula C23H23F6N3S and molecular weight 487.50 g/mol, is a CATO reference standard with documented purity and traceability.
1-(3,5-Bis(trifluoromethyl)phenyl)-3-((1S,2S)-2-(isoindolin-2-yl)cyclohexyl)thiourea (C23H23F6N3S) contains a nitrogen-containing heterocyclic scaffold, a nitrile group, sulfur-containing functionality, fluorine substitution. Halogen substitution raises its density and boiling point, its high carbon-to-hydrogen ratio confers good lipid solubility; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
As a certified reference material (CRM), 1-(3,5-Bis(trifluoromethyl)phenyl)-3-((1S,2S)-2-(isoindolin-2-yl)cyclohexyl)thiourea meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C23H23F6N3S |
| Molecular Weight | 487.50 g/mol |
| Purity | 97%+ |
| Storage | Store at room temperature, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 11.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2003 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 3 |
| Sulfur Atoms | 1 |
Related Bis Standards
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- 3-Methyl-4-[3-(trifluoromethyl)benzoyl]-1-{[4-(trifluoromethyl)phenyl]methyl}-1,2,3,4-tetrahydroquinoxalin-2-one (CAS 317833-58-2)
Recommended Standards
- (1R,3S,5S,8AS)-1,3-bis(2,3-dihydrobenzo[b][1,4]dioxin-6-yl)-5-phenyltetrahydrooxazolo[4,3-c][1,4]oxazin-8(3H)-one (CAS 491833-25-1)
- 2-((6R,8R,8aS)-6-(benzyloxy)-8-hydroxy-2-phenylhexahydropyrano[3,2-d][1,3]dioxin-7-yl)isoindoline-1,3-dione (CAS 80035-33-2)
- 2-Naphthylmethyl 2-acetamido-3-4-6-tri-O-acetyl-2-deoxy-β-D-glucopyranoside (CAS 190181-66-9)
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- N-(4-Ethoxyphenyl)-4-fluorobenzenesulfonamide (CAS 91308-53-1)
- Ethyl 2-(piperidin-4-yloxy)acetate (CAS 167844-03-3)
- 1-(Benzyloxy)-5-bromo-3-fluoro-2-nitrobenzene (CAS 2489407-62-5)
- 2-(2-Chlorophenyl)ethanamine (CAS 13078-80-3)
- (2-(Cyanomethoxy)phenyl)boronic acid (CAS 947533-29-1)
- 4-[4-(2-Methoxy-ethyl)-4H-[1,2,4]triazol-3-yl]-piperidine dihydrochloride (CAS 1361114-92-2)
- 5-Methyl-4-((p-tolyloxy)methyl)thiophene-2-carbaldehyde (CAS 869950-36-7)
- 5-fluoro-1H-pyrrolo[2,3-b]pyridine-2-carboxylic acid (CAS 920978-94-5)
- (2R,3S,4S,5R,6R)-2-(hydroxymethyl)-6-isopropoxytetrahydro-2H-pyran-3,4,5-triol (CAS 5391-17-3)
- Ginseng Tetrapeptide (CAS 178553-95-2)
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