4-Cyclopropyl-5-iodo-1-((2-(trimethylsilyl)ethoxy)methyl)-1H-imidazole CAS 2803476-11-9
| CAS No. | 2803476-11-9 |
| Molecular Formula | C12H21IN2OSi |
| Molecular Weight | 364.30 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
4-Cyclopropyl-5-iodo-1-((2-(trimethylsilyl)ethoxy)methyl)-1H-imidazole (CAS 2803476-11-9) is a high-purity analytical reference standard with the molecular formula C12H21IN2OSi and a molecular weight of 364.30 g/mol.
The molecular framework of 4-Cyclopropyl-5-iodo-1-((2-(trimethylsilyl)ethoxy)methyl)-1H-imidazole (C12H21IN2OSi) is characterized by an amide group, a hydroxyl group, an ether linkage, iodine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C12H21IN2OSi |
| Molecular Weight | 364.30 g/mol |
| Appearance | White to pale yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 3.0 |
| UV Absorption | UV-absorbing |
| CAS Registry Year (est.) | 2003 |
| Halogen Content | I-containing |
| Nitrogen Atoms | 2 |
Related Cyclopropyl Standards
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Recommended Standards
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- 612-15-7 G0I9DYE185 2-Vinylanisole Benzene, 1-ethenyl-2-methoxy- o-Vinylanisole Anisole, o-vinyl- EINECS 210-294-4 1-Ethenyl-2-methoxybenzene FEMA No. 3248 Methoxystyrene, o- 2-Methoxystyrene 1-Methoxy-2-vinylbenzene UNII-G0I9DYE185 (CAS 612-15-7)
- Semaglutide impurity 193 (CAS CATO-C4X-2226193)
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