4-Bromo-6-fluoro-2-hydroxy-2,3-dihydrobenzofuran-7-carbonitrile CAS 2803822-24-2
| CAS No. | 2803822-24-2 |
| Molecular Formula | C9H5BrFNO2 |
| Molecular Weight | 258.04 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
4-Bromo-6-fluoro-2-hydroxy-2,3-dihydrobenzofuran-7-carbonitrile (CAS 2803822-24-2) is a high-purity analytical reference standard with the molecular formula C9H5BrFNO2 and a molecular weight of 258.04 g/mol.
The molecular framework of 4-Bromo-6-fluoro-2-hydroxy-2,3-dihydrobenzofuran-7-carbonitrile (C9H5BrFNO2) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine/bromine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C9H5BrFNO2 |
| Molecular Weight | 258.04 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 7.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2003 |
| Halogen Content | F/Br-containing |
| Nitrogen Atoms | 1 |
Related Bromo Standards
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Recommended Standards
- 4,4,5,5-Tetramethyl-2-(3,4,5-trifluorophenyl)-1,3,2-dioxaborolane (CAS 827614-70-0)
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- 4,4,5,5-Tetramethyl-2-(2,4,6-trifluorophenyl)-1,3,2-dioxaborolane (CAS 325143-04-2)
- 5,5-Dimethyl-2-(2-(trifluoromethyl)phenyl)-1,3,2-dioxaborinane (CAS 95753-22-3)
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- 2,4,6-Tri-tert-butylbenzaldehyde (CAS 3975-81-3)
- (S)-1-benzyl-5-oxopyrrolidine-3-carboxylic acid (CAS 428518-42-7)
- tert-Butyl 4-(cyclopropylcarbamoyl)piperidine-1-carboxylate (CAS 1016743-04-6)
- 3-((3,4-Dihydro-2H-pyrrol-5-yl)amino)propanoic acid (CAS 5249-19-4)
- 4-Methyl-3-(3-methylbenzenesulfonyl)-1-[(4-methylphenyl)methyl]-6-phenyl-1,2-dihydropyridin-2-one (CAS 321431-52-1)
- 3,6-Dimethoxy-4-pyridazinecarboxylic acid ethyl ester (CAS 262353-17-3)
- 2-Benzyloxycinnamicacid (CAS 144242-91-1)
- Atrial Natriuretic Peptide (ANP)(1-28) Alpha (Human, Ovine, Canine) (CAS 91917-63-4)
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