| CAS No. | 2805200-69-3 |
| Molecular Formula | C10H7ClFNO |
| Molecular Weight | 211.62 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
6'-Chloro-5'-fluoro-spiro[cyclopropane-1,3'-indoline]-2'-one (CAS 2805200-69-3) is a high-purity analytical reference standard with the molecular formula C10H7ClFNO and a molecular weight of 211.62 g/mol.
Owing to a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution, 6'-Chloro-5'-fluoro-spiro[cyclopropane-1,3'-indoline]-2'-one is typically off-white to pale yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 211.62 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), 6'-Chloro-5'-fluoro-spiro[cyclopropane-1,3'-indoline]-2'-one meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
| Molecular Formula | C10H7ClFNO |
| Molecular Weight | 211.62 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 7.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2003 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 1 |