Methyl 2-(bromomethyl)-6-(trifluoromethyl)nicotinate CAS 280567-87-5
| CAS No. | 280567-87-5 |
| Molecular Formula | C9H7BrF3NO2 |
| Molecular Weight | 298.06 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
Methyl 2-(bromomethyl)-6-(trifluoromethyl)nicotinate (CAS 280567-87-5), molecular formula C9H7BrF3NO2 and molecular weight 298.06 g/mol, is a CATO reference standard with documented purity and traceability.
Owing to a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine/bromine substitution, Methyl 2-(bromomethyl)-6-(trifluoromethyl)nicotinate is typically off-white to pale yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 298.06 g/mol — guide the selection of appropriate sample preparation and analytical techniques. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
As a certified reference material (CRM), Methyl 2-(bromomethyl)-6-(trifluoromethyl)nicotinate meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C9H7BrF3NO2 |
| Molecular Weight | 298.06 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | F/Br-containing |
| Nitrogen Atoms | 1 |
Related Methyl Standards
- Methyl 5-(bromomethyl)-2-(trifluoromethyl)isonicotinate (CAS 1260671-91-7)
- Methyl 2-(bromomethyl)-5-(trifluoromethyl)nicotinate (CAS 1260672-86-3)
- 2-(Bromomethyl)-5-(difluoromethyl)-6-fluoropyridine-3-acetic acid (CAS 1804947-49-6)
- 2-(4-(Bromomethyl)-3-(difluoromethyl)-5-fluoropyridin-2-yl)acetic acid (CAS 1805998-79-1)
- 2-(4-(Bromomethyl)-5-(difluoromethyl)-6-fluoropyridin-3-yl)acetic acid (CAS 1806991-50-3)
- 2-(4-(Bromomethyl)phenyl)thiazole-4-carboxylic acid (CAS 886368-94-1)
- 2-(4-(Bromomethyl)phenyl)thiazole-5-carboxylic acid (CAS 886370-41-8)
- Methyl 4-(bromomethyl)-3,5-dichlorobenzoate (CAS 859212-75-2)
Recommended Standards
- Ethyl 2-bromo-6-(trifluoromethyl)-3-pyridinecarboxylate (CAS 280567-79-5)
- Methyl 2-amino-5-bromo-4-(trifluoromethyl)benzoate (CAS 851045-83-5)
- 3'-Bromo-4'-(trifluoromethoxy)acetanilide (CAS 755030-17-2)
- N-(4-bromo-2-methoxyphenyl)-2,2,2-trifluoroacetamide (CAS 870838-52-1)
- Mazindol-d4 (1.0mg/ml in Acetonitrile) (CAS 1246815-50-8)
- 5-(4-Bromophenyl)pyrimidin-4-amine (CAS 56239-14-6)
- 1-(3-Aminocyclobutyl)urea (CAS 1157046-22-4)
- (5-Bromo-6-(4-methyl-1H-imidazol-1-yl)pyridin-3-yl)boronic acid (CAS 2225169-49-1)
- (R)-(+)-α-Methylbenzyl Isocyanate (CAS 33375-06-3)
- Abacavir Sulfate (CAS 188062-50-2)
- 1-Amino-3-(4-chlorophenyl)propan-2-one hydrochloride (CAS 93102-99-9)
- 7-Methylnaphthalene-1-carboxaldehyde, 97% (CAS 63409-06-3)
- 7-Methoxy-1-indanone (CAS 34985-41-6)
- Galanin-Like Peptide (human) trifluoroacetate salt (CAS 245114-99-2)
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