(6-Bromo-2,3-dihydrobenzo[b][1,4]dioxin-2-yl)methanol CAS 280752-78-5
| CAS No. | 280752-78-5 |
| Molecular Formula | C9H9BrO3 |
| Molecular Weight | 245.07 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
(6-Bromo-2,3-dihydrobenzo[b][1,4]dioxin-2-yl)methanol (CAS 280752-78-5), molecular formula C9H9BrO3 and molecular weight 245.07 g/mol, is a CATO reference standard with documented purity and traceability.
Owing to a carboxylic acid group, a hydroxyl group, an ether linkage, bromine substitution, an aromatic ring system, (6-Bromo-2,3-dihydrobenzo[b][1,4]dioxin-2-yl)methanol is typically off-white to pale yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 245.07 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C9H9BrO3 |
| Molecular Weight | 245.07 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | Br-containing |
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Recommended Standards
- (4-Bromo-3-methylphenoxy)acetic acid (CAS 90971-89-4)
- (7-Bromo-2,3-dihydrobenzo[b][1,4]dioxin-2-yl)methanol (CAS 280752-79-6)
- (3-Bromo-4-methoxyphenyl)acetic Acid (CAS 774-81-2)
- (7-Bromo-2,3-dihydrobenzo[b][1,4]dioxin-6-yl)methanol (CAS 926190-70-7)
- 2,4-Diamino-6-diethylamino-1,3,5-triazine (CAS 2073-31-6)
- 4-Bromo-2-chloro-5-(difluoromethyl)-3-fluoropyridine (CAS 1804685-56-0)
- 4-Chloro-2-(1,2,3,4-tetrahydroisoquinolin-1-yl)aniline (CAS 10159-02-1)
- 2-Propenoic acid, 2-methyl-, polymer with 2,3-dibromopropyl 2-propenoate and methyl 2-methyl-2-propenoate (CAS 52664-82-1)
- 6-bromo-3-N-methylpyridine-3,4-diamine (CAS 1218997-22-8)
- 3-((3-Cyano-4-(trifluoromethyl)-5,6,7,8-tetrahydroquinolin-2-yl)thio)propanamide (CAS 905787-17-9)
- 4-Ethoxy-3-(trifluoromethyl)benzamide (CAS 1206593-26-1)
- 2-(2,2,2-Trifluoroethoxy)cyclohexan-1-amine (CAS 929973-23-9)
- 2,4-Dichloro-N-(5-cyano-2-(p-tolylthio)phenyl)benzamide (CAS 303147-04-8)
- D-Ser39-Tirzepatide (CAS CATO-CPTD788679)
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