2-Amino-3-((tert-butyldiphenylsilyl)oxy)-2-methylpropan-1-ol CAS 280753-14-2
| CAS No. | 280753-14-2 |
| Molecular Formula | C20H29NO2Si |
| Molecular Weight | 343.54 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
As a certified reference material (CRM), 2-Amino-3-((tert-butyldiphenylsilyl)oxy)-2-methylpropan-1-ol meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
2-Amino-3-((tert-butyldiphenylsilyl)oxy)-2-methylpropan-1-ol (CAS 280753-14-2) is a high-purity analytical reference standard with the molecular formula C20H29NO2Si and a molecular weight of 343.54 g/mol.
2-Amino-3-((tert-butyldiphenylsilyl)oxy)-2-methylpropan-1-ol (C20H29NO2Si) contains a steroid core, an amide group, a hydroxyl group, an ether linkage. Its high carbon-to-hydrogen ratio confers good lipid solubility, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
Physical & Chemical Properties
| Molecular Formula | C20H29NO2Si |
| Molecular Weight | 343.54 g/mol |
| Appearance | Off-white to pale yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 7.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Nitrogen Atoms | 1 |
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