(2E)-1-(4-Fluorophenyl)-3-(3-nitrophenyl)prop-2-en-1-one CAS 28081-18-7
| CAS No. | 28081-18-7 |
| Molecular Formula | C15H10FNO3 |
| Molecular Weight | 271.24 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including (2E)-1-(4-Fluorophenyl)-3-(3-nitrophenyl)prop-2-en-1-one.
(2E)-1-(4-Fluorophenyl)-3-(3-nitrophenyl)prop-2-en-1-one (CAS 28081-18-7), molecular formula C15H10FNO3 and molecular weight 271.24 g/mol, is a CATO reference standard with documented purity and traceability.
The molecular framework of (2E)-1-(4-Fluorophenyl)-3-(3-nitrophenyl)prop-2-en-1-one (C15H10FNO3) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
CATO manufactures (2E)-1-(4-Fluorophenyl)-3-(3-nitrophenyl)prop-2-en-1-one under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C15H10FNO3 |
| Molecular Weight | 271.24 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 11.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1965 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 1 |
Related E Standards
- (E)-1-(4-fluorophenyl)-3-(4-nitrophenyl)prop-2-en-1-one (CAS 102692-41-1)
- (2E)-3-(2-Fluorophenyl)-1-(3-nitrophenyl)prop-2-en-1-one (CAS 1164552-83-3)
- Methyl 4-(4-fluorophenyl)furo[3,2-c]pyridine-6-carboxylate (CAS 1344701-79-6)
- Methyl 4-(3-fluorophenyl)furo[3,2-c]pyridine-6-carboxylate (CAS 1344702-25-5)
- (E)-3-(4-fluorophenyl)-1-(3-nitrophenyl)prop-2-en-1-one (CAS 1415313-20-0)
- (2E)-3-(2-Fluorophenyl)-1-(4-nitrophenyl)prop-2-en-1-one (CAS 2805-52-9)
- (2E)-3-(3-Fluorophenyl)-1-(3-nitrophenyl)prop-2-en-1-one (CAS 879765-27-2)
- (2E)-3-(3-Fluorophenyl)-1-(4-nitrophenyl)prop-2-en-1-one (CAS 198879-97-9)
Recommended Standards
- (2-(4-(Trifluoromethyl)phenethyl)oxazol-4-yl)methanol (CAS 832730-22-0)
- (1-Methyl-5-phenoxy-3-(trifluoromethyl)-1H-pyrazol-4-yl)methanamine (CAS 956181-65-0)
- 5-(Trifluoromethyl)-2',3',5',6'-tetrahydrospiro[indoline-3,4'-pyran]-2-one (CAS 1968119-40-5)
- C-[2-Methyl-5-(4-trifluoromethoxy-phenyl)-furan-3-yl]-methylamine (CAS 1858255-46-5)
- Ethyl (E)-3-(2,3-dichlorophenyl)acrylate (CAS 154238-78-5)
- 5-chloro-4-ethoxy-2-oxo-1,2-dihydropyridine-3-carbonitrile (CAS 2384302-77-4)
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- 4-(5-Oxo-4,5-dihydro-1H-pyrazol-1-yl)benzenesulfonic acid (CAS 34797-30-3)
- Polygalaxanthone III (CAS 162857-78-5)
- 2-[(2-chloro-5-nitrobenzoyl)amino]-3-methylbutanoic acid (CAS 1396968-84-5)
- Sodium 3-oxobut-1-en-1-olate (CAS 42731-41-9)
- 4,4''-Dimethoxy-5'-(4-methoxyphenyl)-1,1':3',1''-terphenyl (CAS 7509-20-8)
- Glucagon receptor antagonists-2 (CAS 202917-18-8)
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