Ethyl 7-chloro-8-fluoro-4-hydroxy-2-oxo-1,2-dihydro-1,6-naphthyridine-3-carboxylate CAS 2808243-26-5
| CAS No. | 2808243-26-5 |
| Molecular Formula | C11H8ClFN2O4 |
| Molecular Weight | 286.64 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
CATO manufactures Ethyl 7-chloro-8-fluoro-4-hydroxy-2-oxo-1,2-dihydro-1,6-naphthyridine-3-carboxylate under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
CATO supplies Ethyl 7-chloro-8-fluoro-4-hydroxy-2-oxo-1,2-dihydro-1,6-naphthyridine-3-carboxylate (CAS 2808243-26-5), a certified reference material (molecular formula C11H8ClFN2O4, MW 286.64 g/mol) for analytical method development and quality control.
Ethyl 7-chloro-8-fluoro-4-hydroxy-2-oxo-1,2-dihydro-1,6-naphthyridine-3-carboxylate (C11H8ClFN2O4) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution. It is notably hygroscopic, halogen substitution raises its density and boiling point, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
Physical & Chemical Properties
| Molecular Formula | C11H8ClFN2O4 |
| Molecular Weight | 286.64 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2003 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 2 |
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Recommended Standards
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- Oxazol-5(4H)-one (CAS 497-24-5)
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- 5-((3-(Trifluoromethyl)phenyl)amino)-1,6-dihydro-[1,1'-biphenyl]-3(2H)-one (CAS 1020252-08-7)
- N-(3,5-Difluorophenyl)-4-methyl-1,2,3-thiadiazole-5-carboxamide (CAS 724435-68-1)
- 9,10-Dichloro-2,6(7)-bis(bromomethyl)anthracene (CAS 1216907-09-3)
- 6-(1H-Imidazol-4-yl)pyrimidin-4(1H)-one (CAS 840529-42-2)
- 3-(Dimethylamino)-1-(6-hydroxy-4,7-dimethoxy-1-benzofuran-5-yl)prop-2-en-1-one (CAS 76301-27-4)
- Des-Ala21-Tirzepatide (CAS CATO-CPTD788952)
Why CATO?
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