4-(3,4-Dimethyl-2,5-dioxo-3-phenylpyrrolidin-1-yl)benzenesulfonamide CAS 28103-55-1
| CAS No. | 28103-55-1 |
| Molecular Formula | C18H18N2O4S |
| Molecular Weight | 358.41 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of 4-(3,4-Dimethyl-2,5-dioxo-3-phenylpyrrolidin-1-yl)benzenesulfonamide is closely related to a flavonoid core, an amide group, a sulfone group, a hydroxyl group, an ether linkage in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
4-(3,4-Dimethyl-2,5-dioxo-3-phenylpyrrolidin-1-yl)benzenesulfonamide (CAS 28103-55-1), molecular formula C18H18N2O4S and molecular weight 358.41 g/mol, is a CATO reference standard with documented purity and traceability.
The molecular framework of 4-(3,4-Dimethyl-2,5-dioxo-3-phenylpyrrolidin-1-yl)benzenesulfonamide (C18H18N2O4S) is characterized by a flavonoid core, an amide group, a sulfone group, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO manufactures 4-(3,4-Dimethyl-2,5-dioxo-3-phenylpyrrolidin-1-yl)benzenesulfonamide under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C18H18N2O4S |
| Molecular Weight | 358.41 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 11.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1965 |
| Nitrogen Atoms | 2 |
| Sulfur Atoms | 1 |
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Recommended Standards
- 4-(3,4-Dimethoxyphenyl)-3-methyl-1-(phenylsulfonyl)-1H-pyrazole (CAS 321526-10-7)
- 4-(5-(4-Methoxyphenyl)-3-(thiophen-2-yl)-4,5-dihydro-1H-pyrazol-1-yl)-4-oxobutanoic acid (CAS 332390-97-3)
- 3-Amino-N-(1,5-dimethyl-3-oxo-2-phenyl-2,3-dihydro-1H-pyrazol-4-yl)-benzenesulfonamide (CAS 379254-54-3)
- 4,5-Dimethoxy-2-(trimethylsilyl)phenyl Trifluoromethanesulfonate (CAS 866252-52-0)
- 2-Ethyltetrahydrofuran-3-amine (CAS 1500657-23-7)
- 4-Methylpent-4-en-1-yl 4-methylbenzenesulfonate (CAS 25163-50-2)
- N-(4-((phenylsulfinyl)methyl)phenyl)-4-(trifluoromethyl)benzamide (CAS 956263-13-1)
- tert-Butyl 7-(hydroxymethyl)-6,7-dihydropyrazolo[1,5-a]pyrazine-5(4H)-carboxylate (CAS 1823856-64-9)
- N-(4-(5-Mercapto-4-(p-tolyl)-4H-1,2,4-triazol-3-yl)phenyl)benzenesulfonamide (CAS 917747-41-2)
- (1-(4-Methoxybenzyl)cyclobutyl)methanamine hydrochloride (CAS 1439902-22-3)
- Cistanoside A (CAS 93236-42-1)
- PDI26-Br (CAS 1015473-19-4)
- Moxifloxacin Impurity 176 (CAS 2102950-42-3)
- Semaglutide impurity 257 (CAS CATO-C4X-2226257)
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