3-methylpyridine-2-sulfonyl chloride CAS 281221-72-5
| CAS No. | 281221-72-5 |
| Molecular Formula | C6H12ClNO2S |
| Molecular Weight | 197.68 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
3-methylpyridine-2-sulfonyl chloride (CAS 281221-72-5), molecular formula C6H12ClNO2S and molecular weight 197.68 g/mol, is a CATO reference standard with documented purity and traceability.
3-methylpyridine-2-sulfonyl chloride (C6H12ClNO2S) contains an amide group, a sulfone group, a carboxylic acid group, a hydroxyl group, an ether linkage, chlorine substitution. Halogen substitution raises its density and boiling point, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
As a certified reference material (CRM), 3-methylpyridine-2-sulfonyl chloride meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C6H12ClNO2S |
| Molecular Weight | 197.68 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 1.0 |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 1 |
| Sulfur Atoms | 1 |
Related methylpyridine Standards
- 3-methylpyridine-4-sulfonyl chloride (CAS 1060801-61-7)
- 2-methylpyridine-3-sulfonyl chloride (CAS 872001-95-1)
- 6-methylpyridine-3-sulfonyl chloride (CAS 478264-00-5)
- 2-Methylpyridine-4-sulfonyl chloride (CAS 1025509-77-6)
- 5-Methylpyridine-2-sulfonyl chloride (CAS 179400-16-9)
- 4-Methylpyridine-2-sulfonyl Chloride (CAS 341008-95-5)
- 4-Methylpyridine-3-sulfonyl Chloride (CAS 372198-42-0)
- 5-Methylpyridine-2,4-dicarboxylic acid (CAS 1033203-39-2)
Recommended Standards
- 3-methylpiperidine-1-sulfonyl chloride (CAS 627887-46-1)
- 4-(2-Chloroethyl)thiomorpholine 1,1-dioxide (CAS 55160-66-2)
- 3-((4-Chlorophenyl)thio)propanenitrile (CAS 5307-86-8)
- 4-Chloro-2,5-dimethylphenylisothiocyanate (CAS 23163-96-4)
- (Z)-3-(4-(Dimethylamino)pyridin-1-ium-1-yl)-1,4-dimethoxy-1,4-dioxobut-2-ene-2-thiolate (CAS 2417676-90-3)
- 5,7-Difluoro-1-methyl-1,2,3,4-tetrahydroisoquinoline hydrochloride (CAS 1384556-57-3)
- 1-Butyl-1H-benzimidazole-2-carbaldehyde (CAS 430470-84-1)
- 2-Amino-5-formylthiophene-3-carbonitrile (CAS 68935-75-1)
- 2,6-Dibromobenzene-1,4-diol (CAS 3333-25-3)
- Methyl 3-[(E)-[(dimethylamino)methylidene]amino]-4-(4-fluorophenyl)thiophene-2-carboxylate (CAS 1334509-64-6)
- Methyl 5-(Bromomethyl)furan-2-carboxylate (CAS 70117-25-8)
- Ethyl (5-chloro-2-methyl-4-sulfamoylphenyl)carbamate (CAS 35442-35-4)
- (4-Chlorophenyl)(2-chloropyridin-3-yl)methanone (CAS 80099-85-0)
- Tirzepatide Impurity 17 (CAS CATO-C4X-324017)
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