4-[(Diethoxyphosphoryl)methyl]benzoic acid CAS 28149-48-6
| CAS No. | 28149-48-6 |
| Molecular Formula | C12H17O5P |
| Molecular Weight | 272.23 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
4-[(Diethoxyphosphoryl)methyl]benzoic acid (CAS 28149-48-6) is a high-purity analytical reference standard with the molecular formula C12H17O5P and a molecular weight of 272.23 g/mol.
4-[(Diethoxyphosphoryl)methyl]benzoic acid (C12H17O5P) contains a phosphate ester group, a carboxylic acid group, a hydroxyl group, an ether linkage, an aromatic ring system. It is notably hygroscopic, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C12H17O5P |
| Molecular Weight | 272.23 g/mol |
| Appearance | Off-white to pale yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), keep sealed and dry |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 4.5 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1965 |
Related Diethoxyphosphoryl Standards
- Methyl 3-(diethoxyphosphoryl)benzoate (CAS 107658-35-5)
- Phenyl 2-(diethoxyphosphoryl)acetate (CAS 3699-64-7)
- 2-(((Diethoxyphosphoryl)methyl)thio)ethyl acetate (CAS 141650-97-7)
- Ethyl 2-(diethoxyphosphoryl)-2-ethoxyacetate (CAS 13676-06-7)
- 1-((Diethoxyphosphoryl)oxy)ethyl butyrate (CAS 213262-84-1)
- Ethyl 2-(diethoxyphosphoryl)-3-methylbutanoate (CAS 35051-50-4)
- Ethyl 2-(diethoxyphosphoryl)pentanoate (CAS 35051-49-1)
- Ethyl 5-(diethoxyphosphoryl)pentanoate (CAS 2323-74-2)
Recommended Standards
- 3-(Trifluoromethyl)-7,8,9,10-tetrahydro-5H-pyrazino[1,2-a]pyrido[3,2-e]pyrazin-6(6aH)-one (CAS 2820001-13-4)
- 4-Amino-6-((4-fluoro-1H-indol-5-yl)oxy)pyrimidine-5-carbaldehyde (CAS 919485-93-1)
- 2-(3-Fluorophenyl)-5,7-dihydroxy-4H-chromen-4-one (CAS 957131-86-1)
- 4-Amino-6-((6-fluoro-1H-indol-5-yl)oxy)pyrimidine-5-carbaldehyde (CAS 919485-94-2)
- 2,3,4,5-Tetrafluoro-6-hydroxybenzaldehyde (CAS 502762-93-8)
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- (1S,2S)-(+)-Thiomicamine 99% (CAS 36624-58-5)
- 7791-20-0 T8365BUD85 Nickel chloride hexahydrate Nickel(II) chloride, hexahydrate (1:2:6) Nickel chloride (NiCl2), hexahydrate CCRIS 3731 Nickel dichloride hexahydrate Nickel(II) chloride hexahydrate UNII-T8365BUD85 Nickel chloride hexahydrate [Nickel and nickel compounds] (CAS 7791-20-0)
- Peptide Impurity 64 (CAS CATO-CPTD788964)
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