5-(2,2-Difluoroethyl)pyridazin-3(2H)-one CAS 2817636-99-8
| CAS No. | 2817636-99-8 |
| Molecular Formula | C6H6F2N2O |
| Molecular Weight | 160.12 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
CATO supplies 5-(2,2-Difluoroethyl)pyridazin-3(2H)-one (CAS 2817636-99-8), a certified reference material (molecular formula C6H6F2N2O, MW 160.12 g/mol) for analytical method development and quality control.
The molecular framework of 5-(2,2-Difluoroethyl)pyridazin-3(2H)-one (C6H6F2N2O) is characterized by an amide group, a hydroxyl group, an ether linkage, fluorine substitution, an aromatic ring system. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO manufactures 5-(2,2-Difluoroethyl)pyridazin-3(2H)-one under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C6H6F2N2O |
| Molecular Weight | 160.12 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2003 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 2 |
Related Difluoroethyl Standards
- 1-(2,2-Difluoroethyl)-1h-pyrazole-4-carbaldehyde (CAS 1006462-72-1)
- 1-(2,2-Difluoroethyl)-1h-pyrazole-3-carbaldehyde (CAS 1310379-50-0)
- 2-(1,1-Difluoroethyl)-4H-pyran-4-one (CAS 1353572-37-8)
- 6-(1,1-Difluoroethyl)pyrimidin-4(3H)-one (CAS 1816998-60-3)
- 1-(1,1-Difluoroethyl)-2-fluorobenzene (CAS 1138445-14-3)
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- 2,2-Difluoroethyl methanesulfonate (CAS 163035-65-2)
- 1-(1,1-Difluoroethyl)-4-fluorobenzene (CAS 55805-03-3)
Recommended Standards
- 4-Ethoxy-3,4-dioxobutanoic acid (CAS 7597-72-0)
- 5-(Difluoromethyl)-2-methoxypyrimidine (CAS 2128733-64-0)
- 4,5-Difluoro-2-methoxyphenol (CAS 246029-17-4)
- 5-(Hydroxymethyl)-2-oxotetrahydrofuran-3-carboxylic acid (CAS 93929-51-2)
- 1-(2-Hydroxyethyl)-3-methyl-1h-pyrazolo[3,4-b]pyridine-5-carboxylic acid (CAS 926250-42-2)
- (R)-N-(1-(4-formylphenyl)ethyl)methanesulfonamide (CAS 1448682-03-8)
- Hydroxy Tipelukast (CAS 1027597-04-1)
- N,O-Dimethyl-N-(9-methyl-9H-purin-6-yl)hydroxylamine (CAS 89204-70-6)
- 2-(Trifluoromethyl)azetidine (CAS 1040331-55-2)
- 1-{4-[(2,2-difluoroethane)sulfonyl]phenyl}ethan-1-one (CAS 1354952-58-1)
- (2,2-Difluoroethyl)glycine (CAS 1179601-53-6)
- N-trans-BOC-(3S)-Fluoropyrrolidine (CAS 479253-00-4)
- ((6-(Methylamino)-1,3,5-triazine-2,4-diyl)bis(methylazanediyl))dimethanol (CAS 104880-54-8)
- (Des-His1,Glu?)-Glucagon (1-29) amide (human, rat, porcine) (CAS 110084-95-2)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
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- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com