5-Aminomethyl-2-trifluoromethyl-pyrimidin-4-ylamine CAS 2822-73-3
| CAS No. | 2822-73-3 |
| Molecular Formula | C6H7F3N4 |
| Molecular Weight | 192.14 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
As a certified reference material (CRM), 5-Aminomethyl-2-trifluoromethyl-pyrimidin-4-ylamine meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
5-Aminomethyl-2-trifluoromethyl-pyrimidin-4-ylamine (CAS 2822-73-3), molecular formula C6H7F3N4 and molecular weight 192.14 g/mol, is a CATO reference standard with documented purity and traceability.
The molecular framework of 5-Aminomethyl-2-trifluoromethyl-pyrimidin-4-ylamine (C6H7F3N4) is characterized by a nitrile group, fluorine substitution, an aromatic ring system. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C6H7F3N4 |
| Molecular Weight | 192.14 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1957 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 4 |
Related Aminomethyl Standards
- 2-(Aminomethyl)-5-(trifluoromethyl)pyridin-3-ol (CAS 1256788-42-7)
- 5-(Aminomethyl)-4-(trifluoromethyl)pyrimidin-2-amine (CAS 1260783-73-0)
- 2-(Aminomethyl)-6-(trifluoromethyl)pyridin-4-ol (CAS 1393555-29-7)
- 6-(Aminomethyl)-4-(trifluoromethyl)pyridin-2(1H)-one (CAS 1393566-05-6)
- 2-(Aminomethyl)-3-(difluoromethyl)-4-fluoro-5-hydroxypyridine (CAS 1804425-32-8)
- 2-(Aminomethyl)-3-(difluoromethyl)-6-fluoro-5-hydroxypyridine (CAS 1805504-12-4)
- 2-(Aminomethyl)-5-(difluoromethyl)-6-fluoro-3-hydroxypyridine (CAS 1805504-38-4)
- 2-(Aminomethyl)-3-(difluoromethyl)-5-fluoro-6-hydroxypyridine (CAS 1805580-22-6)
Recommended Standards
- 5,6-Dimethyl-2-(trifluoromethyl)pyrimidin-4-ol (CAS 685542-44-3)
- 5-Methoxy-6-(trifluoromethyl)pyridin-3-amine (CAS 941606-51-5)
- 5-((4-Amino-1,2,5-oxadiazol-3-yl)amino)-1H-1,2,3-triazole-4-carbonitrile (CAS 728024-38-2)
- 6-(2,2,2-Trifluoroethoxy)-3-pyridinamine (CAS 72617-82-4)
- 6-(2-Methoxyethoxy)nicotinic acid (CAS 894802-20-1)
- 6-methyl-[1,2,4]triazolo[4,3-a]pyridine-3-carboxylic acid (CAS 1159830-54-2)
- N-[(4-Bromophenyl)methyl]-N,N-dimethyl-ethane-1,2-diamine (CAS 99862-34-7)
- 3-Chloro-2H-pyrazolo[4,3-c]pyridine (CAS 1357946-64-5)
- (R)-tert-Butyl 2-(methylcarbamoyl)pyrrolidine-1-carboxylate (CAS 785825-41-4)
- 4-Amino-5-methyl-1-(methyl-d3)-2-phenyl-1,2-dihydro-3H-pyrazol-3-one (CAS 1329792-51-9)
- (2-Propoxy-5-(trifluoromethyl)pyridin-3-yl)boronic acid (CAS 1218790-63-6)
- 1-((6-Hydrazinylpyridazin-3-yl)(methyl)amino)propan-2-ol (CAS 64000-73-3)
- 390362-53-5 Buxbodine D C28H46N2O W1071 (CAS 390362-53-5)
- Peptide 6A (H-6905.0005) (CAS 73549-32-3)
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