(2-oxotetrahydrofuran-3-yl)triphenylphosphonium bromide CAS 28228-78-6
| CAS No. | 28228-78-6 |
| Molecular Formula | C22H20O2P |
| Molecular Weight | N/A |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
(2-oxotetrahydrofuran-3-yl)triphenylphosphonium bromide (CAS 28228-78-6), molecular formula C22H20O2PBr and molecular weight 427.28 g/mol, is a CATO reference standard with documented purity and traceability.
The molecular framework of (2-oxotetrahydrofuran-3-yl)triphenylphosphonium bromide (C22H20O2PBr) is characterized by a steroid core, organophosphorus functionality, a hydroxyl group, an ether linkage, bromine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO manufactures (2-oxotetrahydrofuran-3-yl)triphenylphosphonium bromide under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C22H20O2P Br |
| Molecular Weight | 427.28 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at room temperature, protect from light |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 12.5 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1965 |
| Halogen Content | Br-containing |
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Recommended Standards
- Ethyl 2-(3-formyl-4-nitrophenoxy)acetate (CAS 105728-02-7)
- Hexanoic acid, 3,5,5-trimethyl-, copper(2+) salt (2:1) (CAS 35206-70-3)
- 7-Methoxychromane-3-carbaldehyde (CAS 1083274-06-9)
- 1-(3,5-Difluoro-2-(isopentyloxy)phenyl)-2,2,2-trifluoroethan-1-one (CAS 1443344-37-3)
- 2-Amino-7,8-dihydro-5H-pyrano[4,3-b]pyridin-5-one (CAS 2673369-36-1)
- 2,6-Bis(2’,2’-dimethylpropionyl)pyridine (CAS 156022-06-9)
- 2,6-Dibromo-3-(iodomethyl)pyridine (CAS 58596-61-5)
- 2-(bromomethyl)-4-fluoro-6-(trifluoromethoxy)pyridin-3-amine (CAS 1806185-95-4)
- 1-[4-(5-Bromo-4-methyl-thiazol-2-yl)-piperidin-1-yl]-ethanone (CAS 1361113-49-6)
- Acetyl-Exenatide trifluoroacetate salt (CAS 305815-28-5)
Why CATO?
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